ramadan is considered a holy month in the islamic calendar. during this month, all able-bodied muslim adults refrain from foods, drinks, smoking, and medications from dawn until sunset. in islamic rules, patients and those for whom fasting may have major health risks are exempted from fasting during ramadan. there is still no consensus regarding the effects of ramadan fasting, as a unique oppor...

Original Articles 369 Hormone therapy and risk of cardiovascular outcomes and mortality in women treated with statins Ingegärd Anveden Berglind, MD, PhD, Morten Andersen, MD, PhD, Anna Citarella, PhD, Marie Linder, PhD, Anders Sundström, PhD, and Helle Kieler, MD, PhD Hormone therapy was associated with reduced risks of all-cause mortality and no increased risks of cardiovascular disease in wom...

OBJECTIVE To evaluate differences in first manifestations of cardiovascular disease between men and women in a competing risks framework. DESIGN Prospective population based cohort study. SETTING People living in the community in Rotterdam, the Netherlands. PARTICIPANTS 8419 participants (60.9% women) aged ≥ 55 and free from cardiovascular disease at baseline. MAIN OUTCOME MEASURES Firs...

Chronic obstructive pulmonary disease (COPD) patients are at a high risk of developing cardiovascular diseases. Airflow limitation is a predictor of future risks of hypertension and cardiovascular events. COPD is now understood as a systemic inflammatory disease, with the focus on inflammation of the lungs. An association between inflammation and sympathetic overactivity has also been reported....

The cardiovascular safety of nicotine is an important question in the current debate on the benefits vs. risks of electronic cigarettes and related public health policy. Nicotine exerts pharmacologic effects that could contribute to acute cardiovascular events and accelerated atherogenesis experienced by cigarette smokers. Studies of nicotine medications and smokeless tobacco indicate that the ...

the month of ramadan, as a model of intermittent fasting, is a valuable opportunity to investigate the effects of dietary modifications on human metabolism. fasting improves insulin sensitivity, reduces atherogenic risk, oxidative stress, and inflammation. inflammation plays a key role in the pathogenesis of different disorders including atherosclerosis, metabolic syndrome and cardiovascular di...

The month of Ramadan, as a model of intermittent fasting, is a valuable opportunity to investigate the effects of dietary modifications on human metabolism. Fasting improves insulin sensitivity, reduces atherogenic risk, oxidative stress, and inflammation. Inflammation plays a key role in the pathogenesis of different disorders including atherosclerosis, metabolic syndrome and cardiovascular di...

In the Guidance for Industry from the Food and Drug Administration in 2008, excess cardiovascular risk should be ruled out in trials of all new antidiabetic drugs; however, relatively few studies have focused on cardiovascular safety with antidiabetic drug use. We aimed to examine mortality and cardiovascular risk using a network meta-analysis. We searched the Medline, Embase, Cochrane, and Cli...

BACKGROUND To assess whether the Multidisciplinary Risk Assessment and Management Program for Patients with Diabetes Mellitus (RAMP-DM) led to improvements in biomedical outcomes, observed cardiovascular events and predicted cardiovascular risks after 12-month intervention in the primary care setting. METHODS A random sample of 1,248 people with diabetes enrolled to RAMP-DM for at least 12 mo...

Objective: Literature has confirmed the pathogenic role of cadmium (Cd) and its exposure in the induction of dyslipidemia implicated in the development and increasing incidence of cardiovascular diseases. The current study explored whether polyphenolics isolated from virgin coconut oil (VCO) prevent Cd-induced dyslipidemia and investigate the underlying mechanism of action, in rats. Materials a...