BACKGROUND The efficacy of new antihypertensive drugs has been questioned. We compared the effects of conventional and newer antihypertensive drugs on cardiovascular mortality and morbidity in elderly patients. METHODS We did a prospective, randomised trial in 6614 patients aged 70-84 years with hypertension (blood pressure > or = 180 mm Hg systolic, > or = 105 mm Hg diastolic, or both). Pati...

The aim of the study was to determine cardiovascular drugs utilization and quality of prescribing in Croatia from 2003 to 2008. Data on the outpatient utilization of cardiovascular drugs in Croatia were collected during 2003-2008. Data on the size and number of packages, were obtained from Croatian institute for Health Insurance (CIHI). Based on the data obtained, the numbers of DDD and DDD per...

Background: Reduced productivity due to cardiovascular disease in horses known as the third. Today, a number of drugs with different properties for the treatment of cardiovascular disease in horses which used when considering the need for newer drugs and their side effects are felt. Numerous studies on the effects of cardiovascular drugs and their effects have been carried out to examine the ef...

Background: To study prevalence of cardiovascular diseases and drug utilization review in patients with diseases. Methods: This was a cross-sectional conducted for about 6 months from December 2021 to February Secondary care hospital. Prescriptions 167 were analysed. Patient Case files used extracting necessary data. Results: The collected data analyzed by MS-Excel (Counts Percentages).Cardiova...

We used the Manitoba Health database to examine the relationship between use of inhaled respiratory drugs in people with chronic obstructive respiratory diseases and cardiovascular hospitalizations from 1996 through 2000. The drugs examined were beta agonists [BA], ipratropium bromide IB, and inhaled steroids (ICS). End points were first hospitalizations for supraventricular tachycardia, myocar...

INTRODUCTION Higher price of cardiovascular drugs is one of the reasons for high out-of-pocket expenditure in cardiovascular care. The objective of the study was to determine the price variation in commonly available cardiovascular drugs between public and private hospital pharmacies in Nepal. METHODS A cross-sectional survey was conducted in 3 public and 3 private pharmacies in tertiary-leve...

Cardiovascular toxicity is a major challenge for the pharmaceutical industry and predictive screening models to identify and eliminate pharmaceuticals with the potential to cause cardiovascular toxicity in humans are urgently needed. In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (a...