The use of thrombolytics for the treatment of massive pulmonary embolism with cardiopulmonary resuscitation is being controversially discussed. This is one of the first reports on the successful use of tenecteplase in a 59-year-old man who survived a massive pulmonary embolism after tracheostomy followed by a 30-minute cardiopulmonary resuscitation without cerebral damage. In such a dramatic cl...

Cerebral metabolic alterations during cardiac arrest, cardiopulmonary resuscitation (CPR) and extracorporeal cardiopulmonary life support (ECLS) are poorly explored. Markers are needed for a more personalized resuscitation and post-resuscitation care. Aim of this study was to investigate early metabolic changes in the hippocampal CA1 region during ventricular fibrillation cardiac arrest (VF-CA)...

Introduction: Awareness of pediatric cardiopulmonary resuscitation (CPR) is obligatory for every graduated medical student. In fact, only correct and effective Cardiopulmonary resuscitation can increase the survival rate of patients with cardiopulmonary arrest and since CPR techniques and maneuvers should be done in a specific way for children, it is important to evaluate the knowledge of pedia...

optimize brain perfusion in a patient receiving extracorporeal cardiopulmonary resuscitation (eCPR) after out-of-hospital cardiac arrest (OHCA). A 52-year-old woman (height of 165 cm and weight of 67 kg) had an OHCA secondary to acute myocardial infarction. Th e ambulance arrived on the scene 10 minutes after the call, and mechanical CPR (Lucas; Physio Control Inc., Brussels, Belgium) was initi...

OBJECTIVES To evaluate the use of extracorporeal membrane oxygenation in prolonged cardiopulmonary resuscitation and to estimate how long cardiopulmonary resuscitation can be extended with acceptable results. DESIGN Review of consecutive adult in-hospital cardiopulmonary resuscitation patients without return of spontaneous circulation in 10 mins and with extracorporeal membrane oxygenation re...

Abstract Aim Predicting the return of spontaneous circulation (ROSC) during cardiopulmonary resuscitation in victims cardiac arrest (CA) remains challenging. Cerebral regional oxygen saturation (rSO2) measured is feasible, and higher initial overall values seem associated with ROSC. However, these observations were limited to analysis few small single-centre studies. There a growing number stud...

Permanent brain damage after cardiac arrest and resuscitation is determined by many factors, predominantly arrest (no-flow) time, cardiopulmonary resuscitation (low-flow) time, and temperature. Research since around 1970 into cardiopulmonary-cerebral resuscitation has attempted to mitigate the postischemic-anoxic encephalopathy. These efforts' results have recently shown outcome benefits as doc...

Cardiopulmonary cerebral resuscitation for cardiopulmonary arrest (CPA) is often unsuccessful. Therefore, any method that could decrease the significant mortality associated with CPA would be valuable. Current pharmacologic management of CPA involves the use of epinephrine for increased cardiac output and systemic vasoconstriction; however, this agent is associated with a significant number of ...