we discuss here an uncommon condition of neurogenic hypotension in the context of immunoglobulin light chain (amyloid light-chain) amyloidosis. th e most serious feature was autonomic nervous system impairment, mainly characterized by severe refractory orthostatic hypotension, which became progressively invalidating, forcing the patient to bed. moreover, since the systemic involvement of the di...

during a period of four years between june, is, 1988 to june, is, 1992 one hundred and fourteen patients with congestive heart failure (chf) were admitted to the pediatric department of taleghani general hospital. during the above period, 192 patients with heart disease were hospitalized at this department and chf was the cause of admission in 59.4% of them. congenital heart disease (cho) was t...

Dilated cardiomyopathy is a frequent cause of heart failure and death. Atrial natriuretic peptide (ANP) is a biomarker of dilated cardiomyopathy, but there is controversy whether ANP modulates the development of heart failure. Therefore, we examined whether ANP affects heart failure, cardiac remodeling, function, and survival in a well-characterized, transgenic model of dilated cardiomyopathy. ...

OBJECTIVES To compare HLA distribution in familial and non-familial dilated cardiomyopathy, because a serum marker that could identify families at risk of developing dilated cardiomyopathy should be of use in screening for the disease. PATIENTS 100 patients with dilated cardiomyopathy. METHODS 200 first degree relatives from 56 of the proband families were screened for dilated cardiomyopath...

BACKGROUND Previous studies of the prognosis of patients with heart failure due to cardiomyopathy categorized patients according to whether they had ischemic or nonischemic disease. The prognostic value of identifying more specific underlying causes of cardiomyopathy is unknown. METHODS We evaluated the outcomes of 1230 patients with cardiomyopathy. The patients were grouped into the followin...

Whether apical hypertrophic cardiomyopathy is a variant of classic hypertrophic cardiomyopathy or a separate entity is controversial. This is a case report of an apical hypertrophic cardiomyopathy. The patient was a 67-year-old man associated with giant negative T waves in electrocardiogram and asymmetric apical hypertrophy on echocardiogram. He died of liver cirrhosis and liver cell carcinoma....

As one of the serious complications sepsis, septic cardiomyopathy has gained more and attention, because its high morbidity mortality. With in-depth study cardiomyopathy, several methods have been adopted clinically but poor therapeutic effects due to failure find precise targets. In recent years, microRNAs found be related pathogenesis, diagnosis, treatment via regulating immunity programmed c...

In this article we describe a rare clinical condition of stress cardiomyopathy (takotsubo cardiomyopathy) for which we, despite controversy and lack data, identified the main pathogenic pathways (including direct toxic effect catecholamines on myocardium, catecholamine-mediated myocardial stunning, microcirculation disorders). After systematic review, distinct pathology features new diagnostic ...

takotsubo cardiomypathy is a very rare cardiovascular syndrome leading to myocardial infarction and left ventricular dysfunction in the absence of a detectable coronary artery lesion. it is accepted as reversible left ventricular asynergy occuring typically after an intrinsic adrenergic hyperstimulation. in this report we present takotsubo cardiomyopathy in a 75-year-old patient with multiple a...