Aims: Probiotics are viable and useful microorganisms, which are beneficial factors for human and animal health by altering their microbial flora. Most of the probiotics belong to a large group of bacteria in the human gastrointestinal tract. There are several clinical shreds of evidence that show anti-carcinogenic effects of probiotics through altering digestive enzymes, inhibition of carcinog...

gramme to evaluate the carcinogenic risk of chemicals to humans and to pro duce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in sorne occupations and as a result of human habits) and of exposures to other agents, such as radiation and viruses. With Supplement...

ln 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and...

In 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals. The Monographs programme has since been expanded to include consideration of exposures to complex mixtures of chemicals (which occur, for example, in some occupations and as a result of human habits) and...

Occupational exposure occurs most frequently through direct contact with carcinogenic agents, with any of their active metabolites during absorption (skin, respiratory tract); or during excretion (urinary tract). In the USA, from 2-8% of cancer are attributed to this circumstance. In developing countries emphasis should be made on prevention measures of possible carcinogenic exposure factors, w...

O(6)-Alkylguanine-DNA alkyltransferase (ATase) confers resistance to many of the biological effects of certain classes of alkylating agents by repairing the DNA lesions responsible. The role of ATase in the mutagenic and toxic effects of the carcinogenic and antitumour alkylating agents are of interest in relation to the prevention and treatment of cancer in man. In this commentary we specifica...

Studies have been carried out on the nature of the proteins of mouse skin to which hydrocarbons are bound after topical application. No relation was found between the carcinogenic activities of various hydrocarbons and their inhibition of the incorporation of DL-lysine-2-C 1~ into mouse skin proteins. Salt fractionation of the proteins to which 1,~,5,6-dibenzanthracene-9,10-C TM is bound reveal...