نتایج جستجو برای: carbon catabolite repression

تعداد نتایج: 305443  

2018
Damien J Cabral Jenna I Wurster Peter Belenky

Persistence is a phenomenon during which a small fraction of a total bacterial population survives treatment with high concentrations of antibiotics for an extended period of time. In conjunction with biofilms, antibiotic persisters represent a major cause of recalcitrant and recurring infections, resulting in significant morbidity and mortality. In this review, we discuss the clinical signific...

Journal: :Journal of bacteriology 1994
Y Fujita Y Miwa

Inducer exclusion was not important in catabolite repression of the Bacillus subtilis gnt operon. The CcpA protein (also known as AlsA) was found to be necessary for catabolite repression of the gnt operon, and a mutation (crsA47, which is an allele of the sigA gene) partially affected this catabolite repression.

2014
Yo-Taro Shirai Toru Suzuki Masahiro Morita Akinori Takahashi Tadashi Yamamoto

The carbon catabolite repression 4 (CCR4)-negative on TATA-less (NOT) complex serves as one of the major deadenylases of eukaryotes. Although it was originally identified and characterized in yeast, recent studies have revealed that the CCR4-NOT complex also exerts important functions in mammals, -including humans. However, there are some differences in the composition and functions of the CCR4...

Journal: :The Journal of biological chemistry 2003
Michel Flipphi Peter J I van de Vondervoort George J G Ruijter Jaap Visser Herbert N Arst Béatrice Felenbok

The role of hexose phosphorylating enzymes in the signaling of carbon catabolite repression was investigated in the filamentous fungus Aspergillus nidulans. A d-fructose non-utilizing, hexokinase-deficient (hxkA1, formerly designated frA1) strain was utilized to obtain new mutants lacking either glucokinase (glkA4) or both hexose kinases (hxkA1/glkA4). d-Glucose and d-fructose phosphorylation i...

Journal: :Journal of bacteriology 1966
R T Okinaka W J Dobrogosz

Catabolite repression of 3-galactosidase formation in Escherichia coli ML30 is readily observed when cultures are grown aerobically in media containing glucose or gluconate as carbon and energy sources. If cultures growing exponentially under these conditions are transferred to an anaerobic environment, catabolite repression is temporarily abolished (M. Cohn and K. Horibata, J. Bacteriol. 78:62...

2017
Elisabeth Sonnleitner Konstantin Prindl Udo Bläsi

The RNA chaperone Hfq regulates virulence and metabolism in the opportunistic pathogen Pseudomonas aeruginosa. During carbon catabolite repression (CCR) Hfq together with the catabolite repression control protein Crc can act as a translational repressor of catabolic genes. Upon relief of CCR, the level of the Hfq-titrating RNA CrcZ is increasing, which in turn abrogates Hfq-mediated translation...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1975
W Epstein L B Rothman-Denes J Hesse

Measurements of intracellular adenosine 3':5'-cyclic monophosphate (cAMP) concentrations in E. coli under a variety of conditions show that levels of this nucleotide are well correlated with the rate of synthesis of beta-galactosidase (beta-D-galactoside galactohydrolase, EC 3.2.1.23) in both catabolite repression and transient repression. These results, combined with extensive genetic and in v...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1980
C Guidi-Rontani A Danchin A Ullmann

Pleiotropic carbohydrate-positive pseudorevertants have been isolated from a specific class of rho-crp double mutants of Escherichia coli carrying both defective transcription termination protein, rho, and cyclic AMP receptor protein. The modulation of catabolite repression of beta-galactosidase, amylomaltase, and tryptophanase has been studied in the pseudorevertants. It has been found that th...

Journal: :Journal of general microbiology 1991
T Lodi C Donnini I Ferrero

Catabolite repression by galactose was investigated in several strains of Saccharomyces cerevisiae grown on different carbon sources. Galactose repressed as much as glucose; raffinose was less effective. Full derepression was achieved with lactate. The functions tested were L-lactate ferricytochrome c oxidoreductase, NAD-glutamate dehydrogenase, and respiration. Galactose repression was observe...

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