PURPOSE Perfusion analysis from first-pass contrast enhancement kinetics requires modeling tissue contrast exchange. This study presents a new approach for numerical implementation of the tissue homogeneity model, incorporating flexible distance steps along the capillary (NTHf). METHODS The proposed NTHf model considers contrast exchange in fluid packets flowing along the capillary, incorpora...

vascular lesions rise from abnormalities in blood vessels or endothelial proliferation . capillary hemangiomas are formed by small capillaries surrounded by a layer of endothelial cells in a connective tissue stroma . various treatments are used for these conditions like excisional surgery , sclerotherapy, and recently laser irradiation. in this case study, we report successful treatment of int...

The present study focuses on the behavior of diffusion phenomenon in stenosed capillary-tissue exchange system where the rheology of flowing blood in the capillary is characterized by the generalized Power-law fluid model. Assessment of the severity of the disease could be made possible through the variation of a parameter named as retention parameter. The concentration profile and associated p...

[this article has been retracted for duplicate publication] background: the pathological classification of cryptogenic fibrosing alveolitis has been a matter of debate and controversy for histopathologists. objective: to identify and specify the glycotypes of capillary endothelial cells in usual interstitial pneumonia (uip) compared to those found in normal tissue. methods: sections of formalin...

In acute ischemic stroke, critical hypoperfusion is a frequent cause of hypoxic tissue injury: As cerebral blood flow (CBF) falls below the ischemic threshold of 20 mL/100 mL/min, neurological symptoms develop and hypoxic tissue injury evolves within minutes or hours unless the oxygen supply is restored. But is ischemia the only hemodynamic source of hypoxic tissue injury? Reanalyses of the equ...

In adult dogs following right pneumonectomy (PNX) and receiving all-trans-retinoic acid (RA) supplementation for 4 mo, we found modestly enhanced alveolar-capillary growth in the remaining lung without enhanced resting lung function (J Appl Physiol 96: 1080-1089 and 96: 1090-1096, 2004). Since alveolar remodeling progresses beyond this period and the lipid-soluble RA continues to be released fr...

The literature dealing with the permeability of blood capillaries is voluminous. Nothing appears to have been published, however, concerning the permeability of blood capillary sprouts and newly formed blood capillaries as compared to that of older capillaries. Yet this would seem to be a matter of some importance, since there now appears to be a general agreement (1) that the growth of the ent...

BACKGROUND Much of our current understanding of microvascular permeability is based on the findings of classic experimental studies of blood capillary permeability to various-sized lipid-insoluble endogenous and non-endogenous macromolecules. According to the classic small pore theory of microvascular permeability, which was formulated on the basis of the findings of studies on the transcapilla...