Regulatory guidance for schizophrenia cognition clinical trials requires that the assessment of cognitive change is accompanied by a functionally meaningful endpoint. However, currently available measures are challenged by resistance to change, psychometric weaknesses, and for interview-based assessments, dependence upon the presence of an informant. The aims of the current study were to: 1) as...

De Souza e Silva, E. and H.R. Gail, Performability analysis of computer systems: from model specification to solution, Performance Evaluation 14 (1992) 157-196. Computer systems reliability/availability modeling deals with the representation of changes in the structure of the system being modeled, which are generally due to faults, and how such changes affect the availability of the system. On ...

7 IMPROVING RELIABILITY ON SURFACE TRANSPORT NETWORKS © OECD/ITF 2010 ABSTRACT ITRD NUMBER E145017 Supply chains are, more than ever underpinned by global and, often, just-in-time production and distribution systems. This complexity is echoed in passenger movements, both for business and social purposes. These changing patterns have increased the importance of keeping to schedules. This increas...