Erythema multiforme major was diagnosed in a dog with necrotizing parvoviral enteritis. Skin lesions consisted of ulceration of the footpads, pressure points, mouth, and vaginal mucosa; vesicles in the oral cavity; and erythematous patches on the abdomen and perivulvar skin. Microscopic examination of mucosal and haired skin specimens revealed lymphocyte-associated keratinocyte apoptosis at var...

Viruses have great potential as nanotools in medicine for gene transfer, targeted gene delivery, and oncolytic cancer virotherapy. Here we have studied cell death mechanisms of canine parvovirus (CPV) to increase the knowledge on the CPV life cycle in order to facilitate the development of better parvovirus vectors. Morphological studies of CPV-infected Norden laboratory feline kidney (NLFK) ce...

Canine parvovirus 2 (CPV-2) is the causative agent of acute hemorrhagic enteritis and myocarditis in dogs. A nested polymerase chain reaction (n-PCR) was developed using published pCPV-2ab as external primer set and self designed and custom synthesized pCPV-2N as internal primer set for the detection of canine parvovirus in faecal samples of dogs. Out of 52 faecal samples, 27 and 31 were tested...

Disease is a potential threat to many endangered populations and may originate from sympatric domestic species. This paper describes a cross-sectional serological survey of canine pathogens carried out in domestic (n = 70) and wild dogs (Lycoan pictus) (n = 6), in Tsumkwe District, northeastern Namibia. Evidence of past exposure to canine distemper virus, canine adenovirus and parainfluenza vir...

A study was conducted to evaluate the 3year duration of immunity claim for the canine distemper virus, canine adenovirus type 2, and canine parvovirus fractions in a commercially available modified-live virus vaccine (Duramune Adult, Fort Dodge Animal Health) that was specially formulated to provide a longer duration of immunity than currently available products that are labeled for 1 year of p...

BACKGROUND: Canine Parvovirus (CPV) is one of the major causes of fatal gastroenteritis in young dogs. After emergence of CPV-2, two new variants were reported and named CPV-2a and CPV-2b. In 2001 the newest variant was reported and named CPV-2c. The difference between CPV strains is related to amino acid changes in viral capsid protein (VP2). OBJECTIVES: The aim of the present study was geneti...