The purpose of the present study was to test the hypothesis that extraskeletal calcification regresses in uremic rats after reduction in phosphorus intake and treatment with calcimimetics. Extraosseous calcification was induced in five to six nephrectomized rats fed a high-phosphorus (1.2%) diet who received calcitriol (80 ng/kg ip) every other day for a period of 14 days. Next, dietary phospho...

S: J. MYBURG.H & ]. DE V. DU TOIT. The influence of magnesium sulphate on the absorption, excretiOn and retentiOn of calcmm and phosphorus by sheep fed on phosphate supplemented rations. Onderstepoort]. vet. Res. 37 (1), 1-6 (1970). Eviden~e is l?ut [orward showing that continuous excessive intakes of magnesium sulphate by sheep, for example m dnnkmg water, may result in losses of calcium from ...

Background: The animal is tremendously challenged to maintain calcium homeostasis. Those that fail can develop milk fever, a clinical disorder that is life threatening to the cow and predisposes the animal to a variety of other disorders. Calcium defi ciency disease is often accompanied with a defi ciency in phosphorus in clinical cases. Blood phosphorus status has also been researched because ...

Calciphylaxis is a rare but life-threatening complication seen in dialysis patients. We report a case with calciphylaxis and severe secondary hyperparathyroidism. Sodium thiosulfate (STS) was used for treatment in this case. The painful skin ulcers improved significantly soon after treatment, with a slight reduction in the calcium-phosphorus product. Total parathyroidectomy was carried out 6 mo...

Phosphorus levels correlate with atherosclerosis in both animal models and humans with advanced chronic kidney disease, but whether this relationship exists among individuals with normal kidney function is unknown. This study aimed to determine whether an association exists between phosphorus levels and coronary artery calcium levels in a community-based cohort of 3015 healthy young adults in t...

The object of this study was to ascertain the normal content of calcium and inorganic phosphorus in the blood serum of swine at various ages, and to determine the effect of a high and a low calcium diet on the amount of these elements. Bohstedt and his associates (5) ^ noted differences in these constituents in the blood of pigs when the calcium : phosphorus ratio varied greatly in the rations ...

The present study was undertaken to determine whether improvement of hyperglycemia alters calcium and phosphorus handling, parathyroid hormone (PTH) secretion and bone turnover in patients with non-insulin-dependent diabetes mellitus (NIDDM). We measured serum and urinary mineral levels, serum intact PTH and osteocalcin on admission and at discharge (38 +/- 3 days later, Means +/- SEM) in 28 pa...

For 4 weeks, 3-month old germfree (GF) and conventional (CV) rats were given a semi-synthetic diet sterilized by irradiation with or without 10% of lactose. During the 5th week, 0.2% of titanium oxide (TiO2) was added to the diet and the rats were killed at regular intervals throughout the light/dark cycle. The patterns of TiO2 and 45Ca excretion were similar, indicating that TiO2 was a good ma...

Following the observation by Aub, Bauer, Heath, and Ropes (1), that the thyroid hormone exerts a marked effect upon the excretion of calcium, it became of interest to determine the therapeutic effect of this internal secretion upon the calcium metabolism in tetany. In hyperthyroidism, although the blood calcium and phosphorus levels are essentially normal, the calcium and phosphorus excretions ...

BACKGROUND Both dietary phosphorus restriction and the ingestion of ammonium chloride (NH(4)Cl) given to rats on a high-phosphorus diet have been shown to preserve renal function in the azotaemic rat. Parathyroidectomy also has been reported to preserve renal function and, in addition, to prevent kidney hypertrophy in the remnant kidney model. Our goals were (i) to evaluate in azotaemic rats th...