The saccharomicins A and B, produced by the actinomycete Saccharothrix espanaensis, are oligosaccharide antibiotics. They consist of 17 monosaccharide units and the unique aglycon N-(m,p-dihydroxycinnamoyl)taurine. To investigate candidate genes responsible for the formation of trans-m,p-dihydroxycinnamic acid (caffeic acid) as part of the saccharomicin aglycon, gene expression experiments were...

Front Cover: Caffeic acid is a component of coffee beans and bears catechol functionality. In article number 2100378 by Kotaro Satoh co-workers, caffeic acid-derived styrene monomer amenable to RAFT polymerization, which one the emerging methodologies for polymer synthesis. Combined with protection/deprotection processes, polymerization results in welldefined functional block copolymers consist...

single walled nanotubes (swnt) are common interested nanovehicle to make biosensors more sensitive.carbon nanotubes (cnts) have many distinct properties make them to be exploited to develop the nextgeneration of such nano sensors .the keto-enol tautomerization is one of the most common investigatedsubjects of isomerism in this regards, sensors are devices that are able to detect and change the ...

Using HPLC, the seasonal changes in the phenolic compound content of the leaves of the Gemlik olive cultivar (Olea europaea L) has been investigated with respect to the effects on the alternate bearing of the cultivar. For this purpose, the leaf concentrations of oleuropein, chlorogenic acid, caffeic acid, 3-hydroxycinnamic acid, scopolin and pcoumaric acid were analyzed at 10 day intervals aro...

background propolis is a natural product of bee and caffeic acid phenethyl ester (cape) is a pharmacologically important product of propolis. results cape prevented growth and proliferation of ags human gastric cancer cell line in a concentration-dependent manner with an ic50 of approximately 60 µm by a 24-hour treatment. also cape caused increased induction of apoptosis in ags cells from 1.37 ...

Naoxintong capsule (NXTC) was a famous patent medicine of Traditional Chinese Medicine (TCM) to treat cerebrovascular diseases in China. An LC-MS/MS method was developed for simultaneous determination of 11 major ingredients (paeoniflorin, ecdysterone, amygdalin, mulberroside A, caffeic acid, ferulic acid, salvianolic acid B, astragaloside IV, formononetin, cryptotanshinone, and tanshinone IIA)...

In whole-cell and single-channel patch-clamp recordings from bovine adrenal fasciculata cells, it was discovered that selected caffeic acid derivatives dramatically enhanced the activity of background TREK-1 K+ channels. Cinnamyl 1-3,4-dihydroxy-alpha-cyanocinnamate (CDC), activated TREK-1 when this agent was applied externally to cells or outside-out patches at concentrations of 5 to 10 microM...

Under various concentration conditions of reducing agents during the green synthesis of gold nanoparticles (AuNPs), we obtain the various geometry (morphology and size) of AuNPs that play a crucial role in their catalytic properties. Through both theoretical and experimental approaches, we studied the relationship between the concentration of reducing agent (caffeic acid) and the geometry of Au...

Three phenylpropanoids (ferulic acid, chlorogenic acid, and caffeic acid) are simultaneously separated and determined within 13 min by a new capillary electrophoresis method using 15 mmol/L sodium borate (pH 8.71) as run buffer. The optimum conditions for the separation as well as the analytical characteristics, such as the calibration graph and limit of detection (LOD) for the determination of...

Phenolic composition of different extracts of honeydew melon seeds and their antioxidant activity was determined for the first time. Phenolic compounds were identified using a reversed phase high performance liquid chromatography with diode array detection (HPLC-DAD) method. Results showed the identification of five phenolic compounds in water extract namely gallic acid and its derivative, hydroxyb...