results the prevalence’s of aa, ac and cc genotypes were 55.2%, 24.1% and 20.7% in cad patients and 51.6%, 40.9% and 7.5% in the control subjects, respectively. the frequencies of the c allele were significantly higher in cad patients compared with control groups (p < 0.05). logistic regression analysis revealed a significant association between the c allele and the risk of cad (or = 1.61, 95%c...

Coronary artery disease (CAD) is considered as a chronic inflammatory disease initiated from early childhood. Nuclear factor κB (NF κB) and κB1A (NF κB1A) are the key regulators of inflammatory responses. The NFKB1 -94ATTG ins/del and NFKB1A -826C/T polymorphisms may contribute to the development of CAD.  The aim of the present study was to investigate the association of these polymorphisms wit...

conclusions in the chinese han population that we studied, nafld patients who carry the tnf-α-238 ga polymorphism have an increased risk of developing cad. mechanisms underlying this potentially important association require further investigation. background cardiovascular events account for the main cause of death in patients with non-alcoholic fatty liver disease (nafld), and are largely infl...

BACKGROUND Low concentrations of pyridoxal-5'-phosphate (PLP), the active metabolite of vitamin B-6, are associated with high C-reactive protein (CRP) concentrations. Both low PLP and elevated inflammatory markers, such as high-sensitivity CRP (hs-CRP) and fibrinogen, are related to higher risk of coronary artery disease (CAD). OBJECTIVES The objectives were to evaluate the relation between P...

conclusions in total, application of therapeutic approaches in patients with cad depends on many factors. in our study not only risk factors such as gender, lifestyle, smoking, alcohol abuse, diabetes and hypertension were associated with the incidence of cad, but also they were highly correlated with the severity of the disease. results the mean age of total patients was 58.3 ± 11.5 years (p =...

We examined serum bilirubin and various liver-function enzymes as possible risk factors for angiographically documented coronary artery disease (CAD). The studies involved a "training" set of 619 men for whom complete data on all risk factors considered were available, and a "test" set of 258 men for whom some risk factor data were not available. In both study groups, the liver enzymes were not...

Coronary artery disease (CAD) is the global leading cause of death for both men and women. Risk factors for CAD have been studied extensively and subsequently preventive and treatment measures have been prioritized globally. Nevertheless, the prevalence and mortality rate of CAD remains high. We attempted to identify the most common of the well-known risk factors for developing CAD in a rural p...

AIM To assess the prevalence of coronary artery disease (CAD) in asymptomatic subjects using multidetector computed tomography (MDCT) and its relationships to demographic and clinical risk factors. MATERIAL AND METHOD We enrolled consecutive asymptomatic volunteers with no evidence of ischemic heart disease that underwent MDCT for the early detection of CAD. All MDCT findings were correlated ...

Background: There is limited evidence regarding the risk factors and nutritional patterns in patients with premature coronary artery disease (PCAD). This study aims to investigate the relationship between different dietary patterns and risk factors in patients with PCAD. Methods: This cross-sectional study was conducted on PCAD patients, including men younger than 55 years and women younger tha...