To examine real-world treatment patterns, healthcare resource utilization and costs among third-line (3L) relapsed refractory (R/R) diffuse large B-cell lymphoma (DLBCL) patients in the United States. A retrospective claims analysis was carried out using IBM® MarketScan® Database (Jan 2015-Dec 2019) to assess patterns adult DLBCL receiving 3L treatment. diagnosis of (ICD10 C83.X), ≥ 12 months p...

In the elderly, Alzheimer’s disease (AD) is the most common form of dementia (Hebert et al., 2003). The two pathologies that characterize the disease are the presence of large numbers of intracellular neurofibrillary tangles (NFTs) and extracellular neuritic plaques in the brain (e.g., Braak and Braak, 1991; 1998; Selkoe, 2001). Neurofibrillary tangles consist of hyperphosphorylated, twisted fi...

Measuring Trust: Experiments and Surveys in Contrast and Combination Trust is a concept that has attracted significant attention in economic theory and research within the last two decades: it has been applied in a number of contexts and has been investigated both as an explanatory and as a dependent variable. In this paper, we explore the questions of what exactly is measured by the diverse su...

This paper studies the effect of a Swedish universal child care reform on child health outcomes. We draw on a unique set of merged population register data from the province of Skåne, following over the period 1999-2008. It contains merged information at the individual level from the population register, the income tax register, the medical birth register and the inpatient and outpatient regist...

the present study was conducted to investigate qualitative and quantitative aspects of irrigated wheat production in three major farming systems i.e. peasant, commercial and cooperative systems in kordestan province. accordingly, seven basic hypotheses were tested. the data were drawn from individual interviews with 360 farmers who planted wheat in 2004-2005. the sample was selected using multi...

Alzheimer’s disease (AD) is a tenacious neurodegenerative dementia, characterized clinically by progressive loss of memory, cognitive dysfunction, and behavioral abnormalities, accompanied by the accumulation of intracellular neurofibrillary tangles (NFTs), neuropil threads, as well as extracellular amyloid-beta containing senile plaques, cerebrovascular amyloid-beta deposits, and selective ner...

Amyloid beta protein (Abeta) is the principal component of neuritic plaques in Alzheimer's disease (AD). Abeta is derived from beta amyloid precursor protein (APP) by beta- and gamma-secretases. Beta-site APP cleaving enzyme 1 (BACE1) has been identified as the major beta-secretase. BACE2 is the homolog of BACE1. The BACE2 gene is on chromosome 21 and has been implicated in the pathogenesis of ...

How well do program participants assess program performance ex-post? In this paper we compare participant evaluations based on survey responses to econometric impact estimates obtained using data from the experimental evaluation of the U.S. Job Training Partnership Act. We have two main findings: First, the participant evaluations are unrelated to the econometric impact estimates. Second, the p...

Trust as a concept and empirical measure has attracted significant attention in economic theory and research within the last two decades. However, gaps remain in our understanding of what exactly is measured by the different experimental and survey measures of trust, and how they relate to each other. In this paper, we demonstrate that the commonly used trust game captures trust in strangers, b...

The Internet as a Data Source for Advancement in Social Sciences This paper advocates the use of Internet data for social sciences with a special focus on human resources issues. It discusses the potentials and challenges of Internet data for social sciences and presents a selection of the relevant literature to establish the wide spectrum of topics, which can be reached. Such data represent a ...