trichomoniasis is one of the most common urinary-genital tract disease. the causal agent of trichomoniasis is flagellate protozoan called trichomonas vaginalis. metronidazole and tinidazole are the drug of choice for treatment. carcinogenic and embryo-teratogenic effects of the mentioned drugs and resistance to metronidazole has been reported. according to cytotoxic effects of medicinal herbs i...

A comparative evaluation of the reference National Committee for Clinical Laboratory Standards (NCCLS) broth microdilution method with a novel fluorescent carboxyfluorescein diacetate (CFDA)-modified microdilution method for the susceptibility testing of fluconazole was conducted with 68 Candida strains, including 53 Candida albicans, 5 Candida tropicalis, 5 Candida glabrata, and 5 Candida para...

BACKGROUND The aim of this study was to compare the effects of goal-directed colloid fluid therapy with goal-directed crystalloid and restricted crystalloid fluid therapy on healthy and perianastomotic colon tissue in a pig model of colon anastomosis surgery. METHODS Pigs (n = 27, 9 per group) were anesthetized and mechanically ventilated. A hand-sewn colon anastomosis was performed. The anim...

We have identified two lung carcinoma cell lines, A549 and Calu-1, expressing low levels of the macrophage colony-stimulating factor (CSF-1) receptor (CSF-1R), encoded by the c-fms oncogene. The effect of CSF-1 on the invasive potential of these CSF-1R-positive tumor cell lines and on two other CSF-1R-bearing cell lines, the BT-20 breast carcinoma cell line and the CSF-1 growth-dependent murine...

Dirithromycin antibiotic is a 14-membered lactone ring macrolide and is widely used in medicine to treat many different types of bacterial infections. In the present study, the possible genotoxicity of dirithromycin was evaluated in cultured human lymphocytes by using sister chromatid exchanges (SCEs), chromosome aberration (CA), and micronucleus (MN) tests and also cell proliferation kinetics ...

The aim of the present research was to investigate the genotoxic potency of benzoyl peroxide (BPO), a whitener of flour and cheese, using in vitro sister chromatid exchange (SCE), chromosome aberration (CA), and micronucleus (MN) tests in human peripheral lymphocytes. Cells were exposed to 25, 50, 75, and 100 μg/mL concentrations of BPO for 24 and 48 h. BPO induced SCEs only at the highest conc...

This study investigated the effect of spirulina ethanolic extract (SEE) on quality ram semen during low-temperature liquid storage and relationship between sperm features. Ejaculates were collected from five Djallonké rams, pooled, extended with Tris-egg yolk (TEY) enriched 0 (control), 20 (SEE20), 40 (SEE40), 80 µg/mL (SEE80) SEE to reach concentration 200×106 spz/mL, stored at 4 °C for 72 h. ...

To establish the method for determination of chlorogenic and caffeic acid contents in Prunella vulgaris L., and to investigate the anti-proliferative effect of Prunella vulgaris L. extract on thyroid cancer cells. With chlorogenic and caffeic acids as the quantitative determination targets, their contents in Prunella vulgaris L. are determined by HPLC. Chromatographic column used is Kromasil C1...

Si-Wu-Tang (SWT), a traditional Chinese formula, has been clinically used in the treatment of cutaneous pruritus, chronic inflammation, and other diseases. The present study was carried out to observe the antipruritic and antiinflammatory effects of SWT aqueous extract using compound 48/80 and picryl chloride (PC) models in mice. SWT (500, 1000 mg/kg p.o.) clearly reduced the scratching respons...

OBJECTIVE To determine a pulmonary injury model in rats that is associated with moderate mortality after extubation. DESIGN AND SETTING An experimental study in an animal model of ventilator-induced lung injury in the animal research laboratory in Virgen de las Nieves University Hospital. SUBJECTS AND METHOD A total of 45 male Wistar-Kyoto rats weighing 250-300g received food and water ad l...