today, many companies have multiple channels, such as sales force, direct mail / catalog, internet and broadcast channels, telephone, etc. for providing goods and services to its customers. multiple distribution channels, despite having benefits, several challenges such as the incidence of conflict, allocation of product, free ride some members have being emerged. the aim of this study was to i...

purpose: the aim and objective of this report is to identify the benefits of interactive communication channels and to advice the fmcg business on how these new methods are better than the conventional methods. design/ methodology/approach:  in this research article facts about advertisement and its effectiveness were collected from different surveys conducted by various agencies. mainly second...

ion channels play a major role in the regulation of t cell function in health and disease. in a computer-based model, established to simulate t cells’ membrane potential (vm) generation, we discovered a discrepancy between the simulation and patch-clamp recordings. the predicted vm was more hyperpolarized than the measured vm, indicating that a yet unknown, depolarizing ion current might contri...

One of the common concrete channels in irrigation networks is the semielliptical prefabricated channels. Manning formula is usually used to design these channels. The cross-sectional area and the wetted perimeter are required to be calculated in Manning formula. There are no analytical solutions to directly compute these parameters. Thus, numerical integration methods are inevitably used. In th...

abstract background: improving the patients’ quality of life (qol) after coronary artery bypass grafting (cabg) is one of the main concerns of the treatment team. educational interventions may affect the aspects of qol in various ways. the present study aimed to investigate the effect of education based on the main concepts of logotherapy approach on the cabg patients’ quality of life. material...

the goal of this study was to determine the effects of the l-type calcium channel blockers verapamil and diltiazem on the currents of voltage-gated potassium channel (fkv1.4δn), an n-terminal-deleted mutant of the ferret kv1.4 potassium channel. measurements were made using a two electrode voltage clamp technique with channels expressed stably in xenopus oocytes. the fkv1.4δn currents displayed...

introduction: our previous studies showed that hydroalcoholic extract of leaf of vitis vinifera relaxes the phenylephrine-induced contraction in rat thoracic aorta. this effect was dependent on endothelial integrity and no-cgmp system. the vasorelaxant effect of extract was much lesser on kcl-induced contraction. we, therefore, postulated that k+ channels are involved. the main aim of the prese...

conclusions administration of albumin compared to hes in patients with a normal renal function results in a lower drop of gfr and platelet count, less bleeding and lower rise of serum creatinine. background the ideal strategy to prime the cardiopulmonary bypass (cpb) circuit in adult cardiac surgery is still a matter of debate. objectives in this retrospective study, we examined albumin solutio...