We analyzed the effects of a 4-month resistance (weight lifting) training program followed by a 2-month detraining period in 7 adult McArdle patients (5 female) on: muscle mass (assessed by DXA), strength, serum creatine kinase (CK) activity and clinical severity. Adherence to training was ≥84% in all patients and no major contraindication or side effect was noted during the training or strengt...

We determined the effects of exercise training and detraining on the morphological and mechanical properties of left ventricular myocytes in 4-month-old spontaneously hypertensive rats (SHR) randomly divided into the following groups: sedentary for 8 weeks (SED-8), sedentary for 12 weeks (SED-12), treadmill-running trained for 8 weeks (TRA, 16 m/min, 60 min/day, 5 days/week), and treadmill-runn...

Regular exercise may improve systemic markers of chronic inflammation, but direct evidence and dose-response information is lacking. The objective of this study was to examine the effect and time course of changes in markers of chronic inflammation in response to progressive exercise training (and subsequent detraining). Forty-one sedentary men 45-64 yr of age completed either a progressive 24-...

the aim of this study was to assess the effects of eight weeks of continuous running trainingand four weeks of detraining on lipid peroxidation (mda) and anti-oxidative system response after an acute exercise session. for this purpose, 20 sedentary healthy males were randomly divided into two groups: experimental and control. at the beginning, before and after one acute exercise session, blood ...

To the Editor: Pellicchia et al1 should be congratulated for their unique database and their recent paper on ventricular remodeling after cessation of competitive sports in elite athletes. Their conclusion that ventricular cavity size and wall thickness decreased in all athletes after detraining is consistent with reports in previous longitudinal studies.2,3 However, their observation that vent...

FAULKNER, JOHN A., LEO C.MAXWELL, AND DAVID A. LIEBERMAN. Histochemical characteristics of muscle Jibers from trained and detrained guinea pigs. Am. J. Physiol. 222(4) : 836-840. 1972.~Sixweek-old guinea pigs have nearly 12,000 fibers per plantaris cross section. With aging, some 2,700 fibers were lost. Daily endurance running prevented the loss of fibers and fibers were smaller. Trained animal...

PURPOSE To evaluate the effects of a 12-wk period of aquatic training and subsequent detraining on health-related quality of life (HRQOL) and physical fitness in females with fibromyalgia. METHODS Thirty-four females with fibromyalgia were randomly assigned into two groups: an exercise group, who exercised for 60 min in warm water, three times a week (N = 17); and a control group, who continu...

In the present study, we investigated the effect of swimming training and sudden detraining on learning ability and spatial memory capability and on neurogenesis and brain-derived neurotrophic factor (BDNF) expression in the hippocampus of mice. Male ICR mice were randomly assigned into three groups (n= 15 in each group): the control group, the swimming training group, and the detraining group....