نتایج جستجو برای: burkholderia mallei

تعداد نتایج: 5991  

Journal: :Current Opinion in Infectious Diseases 2017

2011
Gregory C. Whitlock Mark D. Robida Barbara M. Judy Omar Qazi Katherine A. Brown Arpaporn Deeraksa Katherine Taylor Shane Massey Andrey Loskutov Alex Y. Borovkov Kevin Brown Jose A. Cano D. Mitchell Magee Alfredo G. Torres D. Mark Estes Kathryn F. Sykes

Burkholderia are highly evolved Gram-negative bacteria that primarily infect solipeds but are transmitted to humans by ingestion and cutaneous or aerosol exposures. Heightened concern over human infections of Burkholderia mallei and the very closely related species B. pseudomallei is due to the pathogens' proven effectiveness as bioweapons, and to the increased potential for natural opportunist...

Journal: :Journal of clinical microbiology 2006
Ryan T Novak Mindy B Glass Jay E Gee Daniel Gal Mark J Mayo Bart J Currie Patricia P Wilkins

Here we report on the development of a discriminatory real-time assay for the rapid identification of Burkholderia pseudomallei isolates and the evaluation of this assay for sensitivity against related species and detection in spiked human blood samples. The assay targets a 115-base-pair region within orf2 of the B. pseudomallei type III secretion system gene cluster and distinguishes B. pseudo...

barati, Mahmood, dehghan esmatabadi, Mohammad javad , yaghobi moghaddam, Mohammad ali ,

Aim & Background the genus Burkholderia (mallei and pseudomallei species) are classified as dangerous human pathogens. Diagnosing cultures for this bacterium is costly and time consuming and on the other hand it is very dangerous to work with and it is very difficult to access this bacterium. the porpose of this research Design and production of a genetically simulant construct for the detectio...

ژورنال: پژوهش در پزشکی 2011
کمالی, منیره, مردانی, مسعود ,

Abstract Background: This article is a review of Glanders which is a zoo‌notic disease of solipeds caused by a gram negative bacte‌rium named Burkholderia mallei. We used key words glanders, zoonotic disease and bioterrorism for search in PubMed and Google. Finally 53 eligible articles (written in English or Persian) were selected for review. Glanders is highly contagious and often fatal. It...

2009
Heidie Hornstra Talima Pearson Shalamar Georgia Andrew Liguori Julia Dale Erin Price Matthew O’Neill David DeShazer Ghulam Muhammad Muhammad Saqib Abeera Naureen Paul Keim

We collected epidemiologic and molecular data from Burkholderia mallei isolates from equines in Punjab, Pakistan from 1999 through 2007. We show that recent outbreaks are genetically distinct from available whole genome sequences and that these genotypes are persistent and ubiquitous in Punjab, probably due to human-mediated movement of equines.

2009
BART J. CURRIE

The genus Burkholderia is currently composed of many species, but only three are notable pathogens for humans or animals: the former cepacia complex (described in Chapter 220) pseudomallei (the agent of melioidosis), and mallei (the agent of equine glanders). All three are aerobic, nonsporulating, straight or slightly curved gram-negative bacilli that were formerly placed in the genus Pseudomonas.

2017
Sarah M Baker Christopher J H Davitt Natalya Motyka Nicole L Kikendall Kasi Russell-Lodrigue Chad J Roy Lisa A Morici

Burkholderia mallei is a Gram-negative, non-motile, facultative intracellular bacillus and the causative agent of glanders, a highly contagious zoonotic disease. B. mallei is naturally resistant to multiple antibiotics and there is concern for its potential use as a bioweapon, making the development of a vaccine against B. mallei of critical importance. We have previously demonstrated that immu...

2017
Kamal U. Saikh Tiffany M. Mott

PURPOSE OF REVIEW Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen is considered a potential biological threat agent. This review focuses on the most recent literature highlighting host innate immune response to B. ...

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