Three solutions administered by continuous extradural infusion for postoperative analgesia were compared in a randomized, double-blind manner. All patients underwent major abdominal gynaecological surgery and received 0.125% bupivacaine in 0.9% saline, diamorphine in 0.9% saline (0.5 mg in 15 ml) or diamorphine mixed with 0.125% bupivacaine (0.5 mg in 15 ml), at a rate of 15 ml h-1. The bupivac...

Background: Several studies on the reduction of pain with use local anesthetics after laparoscopic hernia surgeries have been published. We aimed to analyze results anesthesia applied patients by retrospectively scanning files who underwent total extraperitoneal hernioplasty for inguinal hernias. Methods: The TEP hernias between March 2019 and November 2022 in Ankara Bilkent city hospital gener...

PURPOSE The aim of this study was to evaluate the effect of bupivacaine irrigated at the surgical bed on postoperative pain relief in laparoscopic cholecystectomy patients. METHODS This study included 60 patients undergoing elective laparoscopic cholecystectomy who were prospectively randomized into 2 groups. The placebo group (n=30) received 20cc saline without bupivacaine, installed into t...

OBJECTIVE To compare the effectiveness of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery. STUDY DESIGN Quasi experimental study. PLACE AND DURATION OF STUDY The Postgraduate Medical Institute, Hayatabad Medical Complex, Peshawar, from February 2006 to August 2007. METHODOLOGY The study was conducted on 60 male children un...

Intraventricular conduction disorders and reentrant arrhythmias in dogs can be produced by high plasma bupivacaine concentrations. The authors' aim was to determine if these conduction disturbances also occurred at moderate plasma bupivacaine concentrations (2.2-3.7 micrograms/ml) when in association with other factors which affect intracardiac conduction, such as hyponatremia and hyperkalemia....

Epidural analgesia is a popular and effective method for pain relief during labor. Bupivacaine is a commonly used local anesthetic for labor epidural analgesia. Ropivacaine is an amino acid local anesthetic that is structurally related to bupivacaine with a similar potency and duration, but ropivacaine has less cardiac toxicity than bupivacaine and produces less motor blockade. These properties...

BACKGROUND Post-thoracotomy pain is the most severe types of postoperative pain. This study compares the effects of intrapleural bupivacaine and morphine on post-thoracotomy pain. METHODS In a double blind clinical trial study, 30 patients candidate for unilateral thoracotomy were randomly divided into bupivacaine and morphine groups. Patients in the morphine group received 0.2 mg/kg morphine...

BACKGROUND In the past, the efficacy of local infiltration of liposomal bupivacaine for total hip arthroplasty (THA) patients was in debate. Therefore, this meta-analysis was conducted to determine whether local infiltration of liposomal bupivacaine provides better pain relief after THA. METHODS We searched Web of Science, PubMed, Embase, and the Cochrane Library databases to the April 2017. ...

Pain is common after a bone graft has been taken from the iliac crest (Kurz, Garfin and Booth 1989). Local wound infiltration with bupivacaine at closure is effective, but relief lasts for only four hours (Todd and Reed 1991). We report a method of infusing bupivacaine which gives effective and lasting analgesia. Patients and methods. Patients requiring iliac crest grafts were randomly selected...

BACKGROUND Unacceptable adverse effects, contraindications to and/or ineffectiveness of World Health Organization step III "pain ladder" drugs causes needless suffering among a population of cancer patients. Successful management of severe cancer pain may require invasive treatment. However, a patient's refusal of an invasive procedure necessitates that clinicians consider alternative options. ...