First-generation adenovirus vectors (FG AdVs) are widely used in basic studies and gene therapy. However, virus-associated (VA) RNAs that act as small-interference RNAs are indeed transcribed from the vector genome. These VA RNAs can trigger the innate immune response. Moreover, VA RNAs are processed to functional viral miRNAs and disturb the expressions of numerous cellular genes. Therefore, V...

BACKGROUND Demand for dialysis treatment exceeds its supply within the Veterans Health Administration (VA), requiring VA to outsource dialysis care by purchasing private sector dialysis for veterans on a fee-for-service basis. It is unclear whether outcomes are similar for veterans receiving dialysis from VA versus non-VA providers. We assessed the extent of chronic dialysis treatment utilizati...

PURPOSE Venous angioma (VA) is the most common congenital abnormality of the intracranial vasculature. This study aimed to investigate the relationship between VA and epilepsy and to identify the characteristics of children with VA and epilepsy. METHODS The records of all patients aged less than 18 years who underwent brain magnetic resonance imaging (MRI) at Pusan National University Hospita...

background: vertebrobasilar arterial territory nourishes one-quarter of human brain. it constitutes some vital and strategic parts of the central nervous system. methods: a number of keywords (vertebral, basilar, artery, and territory) were searched in medline (ovid and pubmed) as well as google, proquest, scopus, cochrane library, and science direct online databases. only articles containing a...

that extend the health care relationship beyond the traditional in-person synchronous encounters that for so long have been the centerpiece of patient/provider interactions. Connected health technologies include telehealth, telemedicine, patient portals, mobile health applications (mHealth), wearable monitoring devices, and other technologies that connect patients to their health care team or h...

Outflow tract ventricular arrhythmias (OT-VA) are common in healthy subjects without structural heart disease (SHD), and generally considered benign. However, athlete-specific data on the clinical meaning of different arrhythmia (VA) morphologies scarce. To assess prevalence SHD as well long-term sports medicine outcomes a cohort athletes with OT-VA undergoing comprehensive diagnostic assessmen...

BACKGROUND Assessment of women veterans' health needs and preferences and their care environment have been identified as a priority research need by the national Veterans Affairs (VA) Women's Health research agenda. Our objective was to identify women veterans' health care preferences and perceptions associated with sole or dual VA health care use. METHODS This cross-sectional study of 1,002 ...

This work introduces an automatic procedure for determining the size of regression class trees for individual speakers using an ensemble of speaker-level features to control the number of transformations, if any, that should be estimated by maximum likelihood linear regression. Experiments with a state-of-the-art speech recognition system that uses this procedure show improvements in word error...

Many questions remain regarding vitamin A (VA) supplementation of infants. Herein we compared direct oral VA supplementation of the neonate and indirect treatment through maternal dietary VA (M-VA) treatment on VA status and kinetics in neonatal rats. Treatments included direct VA combined with retinoic acid (RA) [D-VARA; VA (6 mg/kg) + 10% RA, given orally to neonates on postnatal day (P)2 and...