We have previously presented a building block folding model. The model postulates that protein folding is a hierarchical top-down process. The basic unit from which a fold is constructed, referred to as a hydrophobic folding unit, is the outcome of combinatorial assembly of a set of "building blocks." Results obtained by the computational cutting procedure yield fragments that are in agreement ...

The conceptual design of compliant mechanisms is generally performed using one of two methods: topology optimization or the Pseudo-Rigid-Body Model. In this paper, we present a conceptual design methodology which utilizes a building block approach. The concept of the instant center is developed for compliant mechanisms and is used to characterize the building blocks. The building block characte...

In this paper, a method of low power analog testing is proposed. In spite of having Oscillation Based Built in Self-Test methodology (OBIST), a look up table based (LUT) low power testing approach has been proposed to find out the faulty circuit and also to sort out the particular fault location in the circuit. In this paper an operational amplifier, which is the basic building block in the ana...

This paper proposes a new algorithm to identify and compose building blocks. Building blocks are interpreted as common subsequences between good individuals. The proposed algorithm can extract building blocks from a population explicitly. Explicit building blocks are identified from shared alleles among multiple chromosomes. These building blocks are stored in an archive. They are recombined to...

The objective of this paper is to evaluate the semantic building block-based approach as a means for improving comparability in business process modelling. It is described whether and why the semantic building block-based approach reduces the variations in comparison to traditional modelling approaches. Our argumentation is grounded on the assumption that business process modelling projects in ...

Adding a network interface to a microprocessor-controlledproduct significantly complicates the product design. This paper describes a method of 'rmnimizJng this addedcomplexity by encapsulating the network interface in its own processor and providing a simple, standard internalcommunications interfacebetween the network processor and the host processor. This approach significantly easesproduct ...

hen your gut tells you to run, it is wise to listen. Em-bryonic neural precursor cells do just that, according to De Bellard et al. (page 269), who identify the basis of an avoidance mechanism for migrating neural crest cells. Groups of embryonic neural precursors take separate paths on their way to forming the peripheral nervous system. Vagal cells, which emerge from the neck region, migrate l...