Finger tip patterns of sixty patients of Bronchial Asthma were compared with that of 50 control cases. Higher frequency of whorls was observed in first digit of both generations of bronchial asthma patients in comparison to controls. In all digits the frequency of arches was reduced in both generations of bronchial asthma patients as compared to controls. These findings proved highly significan...

Bronchial Asthma is a major non-communicable disease affecting both children and adults, nearly 262 million people in India suffer from asthma (WHO). It chronic disorder that affects the airways characterized by bronchial hyper-reactivity reversible airway obstruction. could be correlated as Tamak shwasa Ayurveda considered Pranvaha srotho vikara. The Pathya Aahar Vihara, having Vata Kapha alle...

BACKGROUND There are studies indicating that bronchial asthma is often underdiagnosed, while only a little research has been conducted as concerns overdiagnosing asthma. OBJECTIVE We aimed to estimate the number of patients who have been given the wrong diagnosis of asthma. METHODS All patients aged above 18 years who had visited two GPs during 1994 or 1995, with the diagnosis of bronchial ...

To clarify the interrelation between interleukin-2 (IL-2) and soluble IL-2R receptor (sIL-2R), as products of T-cell activation in the bronchial tree of patients with bronchial asthma, we measured the concentration of IL-2, sIL-2R, and the cellular composition in bronchoalveolar lavage (BAL) fluid. We also measured physiologic parameters, including provocation concentration of histamine require...

BACKGROUND Increased proliferation of bronchial smooth-muscle cells may lead to increased muscle mass in the airways of patients with asthma. The antiproliferative effect of glucocorticoids in bronchial smooth-muscle cells in subjects without asthma is mediated by a complex of the glucocorticoid receptor and the CCAAT/enhancer binding protein alpha (C/EBPalpha). We examined the signaling pathwa...

BACKGROUND A very weak relationship has been reported between the health-related quality of life (HRQL) of patients with asthma and their degree of airway hyper-responsiveness (AHR), evaluated in terms of sensitivity. However, this relationship still has not been sufficiently explored for bronchial reactivity indices. OBJECTIVES To analyse the relationship between bronchial reactivity and sen...

The pathogenesis of bronchial asthma is not yet fully understood. Recently much attention has been given to the hypothesis that intracellular free calcium ([Ca2+]i) metabolism is abnormal in various diseases. In this study we investigated whether [Ca2+]i exists abnormally in subjects with bronchial asthma. The [Ca2+]i in 32 treated or untreated subjects with bronchial asthma were compared with ...

Background Asthma is a chronic inflammatory disease in respiratory system and obesity is another inflammatory disease which incidence rate is increasing. Although, many studies have been conducted on severity of asthma and its relationship with obesity, but different results have been obtained. This study aimed to determine a relationship between asthma severity, Body Mass Index (BMI) and pulmo...

Arterial blood gas sampling is a very important investigation in the assessment of a patient’s acidbase status and oxygenation in acute and chronic bronchial asthma. It is the gold standard test which measures amounts of oxygen and carbon dioxide as well as the pH of the blood while it also evaluates the effective delivery of oxygen to the blood by the lungs and effective elimination of the car...

To evaluate whether epithelial damage of airways in asthma could be related to diminished levels of the low molecular weight bronchial leukocyte proteinase inhibitor (BLPI) in airways, we determined BLPI in bronchial washings of 13 asthma patients and 13 healthy subjects, using a sensitive enzyme-linked immunoassay. The patients had asthma due to western red cedar and had bronchial washings don...