Bronchial asthma is characterized by the bronchial hyperresponsiveness and airway obstruction related to airway smooth muscle contraction. Eosinophilic airway inflammation is involved in its pathogenesis. To reproduce the condition, various animal models have been prepared. However, there are many models that do not reflect the spontaneous history of bronchial asthma onset in humans due to the ...

background: pediatric bronchial asthma is associated with considerable morbidity. the study was carried out to examine the association of human leukocyte antigen (hla)- class ii with the disease as we found no similar study on asian indian population. objective: to define the hla-class ii antigens in asian indian pediatric patients with asthma. methods: a total of 103 children with asthma and 1...

The review considers the main groups of drugs used to treat bronchial asthma depending on severity disease. mechanisms action and effectiveness taking anti-asthma drugs, their combinations side effects are covered in detail. Particular attention is paid targeted therapy with biological which aimed at reducing allergic inflammatory response patients severe asthma. This approach allows change nat...

Using hippuryl-L-histidyl-L-leucine as a substrate analog, serum angiotensin converting enzyme (ACE) was spectrophotometrically estimated in patients with bronchial asthma. There were significantly low activities of serum ACE in 115 patients with bronchial asthma irrespective of the presence or absence of acute attack. The activity of serum ACE was reduced more markedly in the chronic type of b...

Chronic airway inflammation, one of the pathophysiologic features of bronchial asthma, is suspected to be responsible for irreversible pathological changes of airways, called airway remodeling. To examine the mechanisms of airway remodeling in asthma, we investigated the expression of epidermal growth factor (EGF) and its receptor immunohistochemically in asthmatic human airways. Airway specime...

The number of senile patients with therapy resistant bronchial asthma, chronic pulmonary emphysema increases due to the habit of smoking and increased number of older people, and these inflammatory pulmonary diseases are the leading causes of death worldwide. Rhinoviruses cause the majority of common colds, and provoke exacerbations of bronchial asthma and chronic pulmonary emphysema. Here, I r...

Local Treatment of Bronchial Asthma with Hydrocorfisone Powder H. HERXHEIMER, M.D., L.R.C.P.&S.Ed. MONICA K. MCALLEN, M.D., M.R.C.P., and D. A. WILLIAMS, M.D., M.SC. F.R.C.P. Bronchial Asthma and Chronic Bronchitis Treated with Hydrocortisone Acetate Inhalations W. H. HELM, M.R.C.P., and F. HEYWORTH, M.B. ........................................................ 765 Inhalation of Hydrocortisone ...