This study investigated the effect of extracts of different composites, glass ionomer cement (GIC)s and compomers on the viability of brine shrimp larvae. Ethanolic extracts of four dental composites (Z-100; Solitaire 2; Filtek P60 and Synergy), a conventional GIC (Ketac-Fil), a resin-modified glass ionomer cement (Vitremer), two compomers (F2000; Dyract AP), and a flowable compomer (Dyract Flo...

The present study revealed the toxic effect of silver nanoparticles (AgNPs) in Artemia nauplii and evaluated the mortality rate, hatching percentage, and genotoxic effect in Artemia nauplii/cysts. The AgNPs were commercially purchased and characterized using field emission scanning electron microscope with energy dispersive X-ray spectroscopy. Nanoparticles were spherical in nature and with siz...

Two new quinoldione alkaloids, methyl 2-(3-hydroxy-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinolin-3-yl)acetate (1) and 3-hydroxy-1-methyl-3-(2-oxopropyl)quinoline-2,4(1H,3H)-dione (2), and two quinolinone alkaloids previously synthesized but first isolated as natural products, N-methylflindersine (3) and 4-hydroxy-3-methoxy-1-methyl-2(1H)-quinolinone (4), were isolated from the stem bark of Micr...

Background and objectives: Ferula gummosa Boiss. (Umbelliferae) is a popular medicinal plant, which is known mostly for therapeutic uses of its oleo-gum-resin (Barijeh in Persian). In the present study, the essential oil of F. gummosa roots was investigated for its phytochemical constituents, antioxidant activity and toxicity potential. Method...

In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado") that could contain useful compounds for the control of tropical diseases. The plant selection was based on existing ethnobotanic information and interviews with local healers. Plant extracts were screened for: (a) molluscicidal activity against Biomphalaria glabrata, (b) toxicity to brine shrimp (Art...

      In the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. Among the ligands tested, diacetyl-bis(N4-methylthiosemicarbazones) (ATSM) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde Bis(N4-methyl)thiosemicarbazone (P...

isolated five known iridoids glycosides (scrophuloside a, harpagoside b, 5-hydroxyloganin, 8-o-acetylharpagide and 6-o-methyl,1-glucopyranosyl catalpol ),one phenyl ethanoid glycoside (verbascoside) and a phenyl ethanol amine (2-(4-chlorobenzyl amino) ethanol ) compound from the methanolic extract of aerial parts of scrophularia oxysepala using by high performance liquid chromatography based on...

the essential oils of the aerial parts of a. armeniaca and a. incana , collected from arasbaran area (east azarbaijan province, iran) were extracted by hydrodistillation and analyzed by gc-ms. in total, 16 and 40 constituents were identified and quantified in the oils of a. armeniaca and a. incana representing 80.5% and 84.6% of the oils, respectively. the essential oil of a. armeniaca was main...

Silver staining of the adult brine shrimp, Artemia salina, revealed that only the metepipodites of the phyllopodia were significantly permeable to chloride and/or silver ions. The metepipodites stained in a reticulated pattern, possibly indicating areas in the cuticle over cells specialized for chloride secretion. Crude homogenates of metepipodites had very high Na/K-ATPase enzyme specific acti...