background: potential association of leptin (lep) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. we investigated whether genetic variations in the lep -2548g/a gene are associated with risk of breast cancer. methods: this case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

In acute leukemia, leukemic infiltration of the breast is extremely rare. We report a case of biphenotypic acute leukemia (BAL) that presented as a breast mass. A 30-year-old woman presented with a 4-month history of a right breast mass with nipple discharge and easy fatigue. She had received chemotherapy and peripheral blood stem cell transplantation for BAL and had been in complete remission ...

conclusion our study suggests that breast mri findings of igm have a wide spectrum. rim enhancement patterns are frequently seen on contrast enhanced images, but the imaging findings are nonspecific and cannot be used definitively to distinguish between benign and malignant lesions. patients and methods a retrospective analysis was conducted on 20 patients with igm who had been diagnosed by nee...

Normal Breast Anatomy and Physiology Presenting symptoms of breast cancer % of total Differential diagnosis of a breast mass Benign Non-infiltrating (in situ) Invasive breast cancer Occult primary Nipple discharge Breast cancer behavior, general comments Mass screening Identification of high-risk groups Risk of Breast Cancer is influenced by endogenous estrogen levels Postmenopausal hormonal re...

background: breast implant associated anaplastic large t- cell lymphoma is a rare type of non-hodgkin lymphoma, with a reported incidence of 0.3% per 100,000 women with breast prosthesis per year. it presents most commonly as a peri-implant seroma, but may also present as a capsular mass, tumor erosion through skin, in a regional lymph node, or found incidentally during revision surgery. case p...

We report a case of woman with a palpable lump on her left breast. On mammography, a huge mass located between the inner and the outer inferior breast quadrants of the left breast was found. The ultrasound examination realized later revealed a heterogeneous mass with smooth and lobulated borders. An MRI was also performed, showing an oval mass with heterogeneous areas of enhancement. Finally, a...

juvenile fibroadenoma is an uncommon histologic variant of fibroadenoma that frequently shows a remarkable and rapid growth. the development of a carcinoma within a fibroadenoma, either in situ or invasive, is a rare condition. we encountered a 36-year-old woman with a palpable mass in the right breast. the radiologic findings were indicative of a fibroadenoma in the breast. sonographic guided ...

conclusions although in our study washout pattern was the most powerful indicator for malignant pathology in non mass like enhancing lesions, more studies with larger sample size needs in this regard. background several studies on the diagnostic efficacy of mri has not real consensus for the accuracy of mri characteristics in non mass like breast lesions, and the number of malignant lesions in ...

Introduction: Of the factors leading to false negative results in mammography is breast tissue density, and by increasing the density of breast tissue in mammography, the mammography sensitivity decreases. On the other hand, increasing the breast tissue density leads to increased risk of breast cancer. Various factors such as inheritance, genetics, hormonal and reproductive factors, and nutriti...

introduction giant fibroadenoma is a rare disease with unknown etiology. during pregnancy, fibroadenomas increase in size and may show lactational histologic changes. high concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. this may be a reason for the significant enlargement in this period. case presentation we presented...