The aim of this study was to evaluate the usefulness of serum (1,3)-beta-D-glucan (BDG) for earlier detection of breakthrough candidemia. We reviewed the medical records of patients with candidemia from January 2008 to March 2013. Serum BDG was measured by Wako turbidimetric assay. During the study period, a total of 147 cases of candidemia were identified, and 31 patients met the criteria for ...

The Q/U Imaging Experiment (QUIET) is an experimental program to make very sensitive measurements of the Cosmic Background Radiation (CMB) polarization from the ground. A key component of this project is the ability to produce large numbers of detectors in order to achieve the required sensitivity. Using a breakthrough in mm-wave packaging at JPL, a polarimeter-on-a-chip has been developed whic...

Abstract A sets of sand column experiments were conducted to investigate the transport and deposition of colloids in water-saturated porous media, and the mechanism of the permeability reduced by transport and deposition of colloids are discussed. The research results show that the breakthrough curves of colloid transport in water-bearing media presented as three stages: “not-yet-breakthrough”,...

Seizures are one of the commonest neurological symptoms seen in children. Recurrent seizures could ensue from epilepsy, febrile seizures, provoked seizures, drug inefficacy or with, or due to unknown or systemic illnesses [1]. A breakthrough seizure is an epileptic seizure that occurs, despite the use of anticonvulsants that have otherwise successfully prevented seizures in the patient. Breakth...

in this study, bimodal meso-porous silica (uvm-7) synthesized and fabricated amino silane modified supports were characterized by powder x-ray diffraction (xrd), n2 adsorption/desorption, transmission electron microscope (tem), elemental analysis and titration. capacity of co2 capture on modified bimodal pore structure silica at 70°c was calculated using breakthrough curves; and it was found th...

background: technetium-99m radioisotope is the backbone of any nuclear medicine institute. this radioisotope is acquired by the elution of molybdenum-99/technetium-99m generator which emits 141 kev gamma ray and having 6.04 hour half-life. occasionally the contents of molybdenum-99 may mix up with elute, which may affect image quality and patients may receive higher doses than recommended. this...

Virological breakthrough is a clinical manifestation in patients infected with chronic hepatitis B (CHB), who undergo treatment with nucleoside/nucleotide analogs (NUCs). The current understanding of the underlying mechanism of virological breakthrough is limited. Ultra‑deep pyrosequencing (UDPS) is a novel and powerful tool used to investigate minor viral variants and viral evolution. The pres...

In July 2012, Congress passed the Food and Drug Administration Safety and Innovation Act (FDASIA). The Advancing Breakthrough Therapies for Patients Act was incorporated into a Title of FDASIA to expedite clinical development of new, potential "breakthrough" drugs or treatments that show dramatic responses in early-phase studies. Using this regulatory pathway, once a promising new drug candidat...

background hepatitis b virus (hbv) infection is a serious public health problem in china and worldwide. mother-to-child transmission is one of hbv’s main transmission routes in highly endemic regions. genome-wide association studies (gwas) identify single nucleotide polymorphisms (snps) at hla loci as associated with hbv infection. however, the mechanisms of hbv perinatal transmission and break...

Recently it has been experimentally demonstrated that non-local (instantaneous) communication between two beams of light (spin direction) can randomly occur. The effect is described as a consequence of the physics of quantum mechanics. Other research has experimentally demonstrated that the zero point radiation/fields (ZPF), which pervade space-time, can effectively be shielded so as to force t...