Abstract Various positron emission tomography (PET) tracers have been developed and extensively studied in the field of neuro-oncology imaging. In management brain tumors, accurate delineation tumor extent, assessment treatment response, detection early recurrence are most important factors. At present, conventional anatomical imaging paired with amino acid tracer PET is recommended modality fo...

Cancer stem cells (CSCs) are suggested as the most dominant causes of recurrence due to their permanent self-renewal and resistance to common cancer treatment in glioblastoma multiform (GBM) which is recognized as the most malignant of brain tumor. It has been indicated that Retinoblastoma-binding protein 5 (RBBP5), a main part of Mixed lineage leukemia protein-1 (MLL1), plays a significant rol...

Background. Although early stage non-small cell lung cancer (NSCLC) has an excellent outcome and correlated with good long-term survival, up to 15 percent of patients still relapse postoperatively and die. This study is conducted to identify prognostic factors that may affect the long-term survival in completely resected N0 NSCLC. Methods. Medical records of 124 patients with completely resecte...

Introduction: Surgical resection and chemotherapy alone have proven to be insufficient in treatment of patients with primary and metastatic brain tumors. As a result, the various forms of radiotherapy, such as external-beam radiation, radiosurgery have become important therapeutic adjuncts. The appearance of a new enhancing lesion after radiation treatment may represent tumor recurrence, radiat...

aim :  this study aimed to compare the recurrence rate, mortality, and morbidity of curative resection of distal adenocarcinoma of the stomach between total gastrectomy (tg) and subtotal gastrectomy (stg). background : the choice between tg and stg for adenocarcinoma of the lower third of the stomach is still a matter of debate and controversy among surgeons. patients and methods : hospital rec...

There is currently no consensus regarding the optimal radiation volume for high-grade glioma (HGG). The brain volume irradiated is associated with the extent of radiation neurotoxicity. When reducing the treatment volume, the risk of geographic tumor miss should be considered. In such cases, the recurrence patterns and, particularly, the rate of marginal tumor recurrence, are important indices ...

INTRODUCTION Current MRI sequences are limited in identifying brain areas at risk for high grade glioma recurrence. We employed intraoperative 3-Tesla functional MRI to assess cerebrovascular reactivity (CVR) after high-grade glioma resection and analyzed regional CVR responses in areas of tumor recurrence on clinical follow-up imaging. METHODS Five subjects with high-grade glioma that underw...