INTRODUCTION Malignant primary brain tumors are one of the most aggressive cancers. Pretreatment serum nonneuronal biomarkers closely associated with postoperative outcomes are of high clinical relevance. The present study aimed to identify potential pretreatment serum biomarkers that may influence oncological outcomes in patients with primary brain tumors. METHODS A total of 74 patients unde...

wilms’ tumor is the most common abdominal tumor of childhood, and its cerebral metastasis is apparently very rare. the authors report an 18-month-old girl with wilms’ tumor and brain metastasis.

background: radiotherapy plays an important role in the management of most malignant and many benign primary central nervous system (cns) tumors. radiotherapy affects both tumor cells and uninvolved normal cells; so, it is important to estimate absorbed dose to organs at risk in this kind of treatment. the aim of this study was to determine the absorbed dose to chiasma, lens, optic nerve, retin...

background: in this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to mahak pediatric cancer treatment and research center (one of the main national referral centers for childhood malignancies in iran) for treatment. materials and methods: this cohort (simple sampling) study consisted of 198 children less than 15 year old with cns tumor refer...

radiation induced sarcoma is a rare but recognized complication of radiotherapy and is associated with poor prognosis, frequently occurs 5 years after completion of treatment. we report radiation-induced sarcoma in a 42 years old male, involving the left parietooccipital scalp region following treatment of brain tumor with craniotomy and post-operative radiation with 60co machine. diagnosis of ...

Background Patients with brain tumor are in risk of depression or depressive symptoms, but the estimated prevalence varies between studies. The aim of this study is to get a proper summarized estimate of depression prevalence in brain tumor patients. Methods Literature search on Pubmed, PsycINFO, and Cochrane library from January 1981 through October 2016. The prevalence of depression or depr...

Understanding brain diseases such as categorizing Brain-Tumor (BT) is critical to assess the tumors and facilitate patient with proper cure per their categorizations. Numerous imaging schemes exist for BT detection, Magnetic Resonance Imaging (MRI), generally utilized because of better quality images reality depending on non-ionizing radiation. This paper proposes an approach detect distinctive...

Glioblastoma is one of the most common brain tumors in adults with poor prognosis, aggressiveness, and treatment resistance. Vasculogenic mimicry (VM) consists of generating vascular-like channels by tumor cells, independent of endothelial angiogenesis. Studies showed in glioblastoma, the proportion of VM to all vascular channels is associated with poor prognosis and higher invasiveness levels....

BACKGROUND Although conventional MR imaging (MRI) is the most widely used non-invasive technique for brain tumor grading, its accuracy has been reported to be relatively low. Advanced MR techniques, such as perfusion-weighted imaging (PWI), diffusion-weighted imaging (DWI), and magnetic resonance spectroscopy (MRS), could predict neoplastic histology, but their added value over conventional MRI...

The ability to accurately distinguish remaining or recurrent high-grade astrocytoma from necrosis or edema following treatment is essential to optimal patient management. Thallium 201 planar gamma-camera imaging has been shown to be helpful in detecting recurrent high-grade astrocytoma; however, due to tissue heterogeneity adjacent to and within tumor, the cellular specificity and quantificatio...