The regional cerebral blood flow (rCBF) and the cerebral vasoreactivity of the patients with depressive disorder were observed by SPECT and acetazolamide stress SPECT test respectively. Eighteen unmedicated depressed patients and nineteen healthy control subjects were included. Baseline SPECT was performed in both patients and control subjects. Acetazolamide stress SPECT test was performed two ...

Periodic lateralized epileptiform discharges (PLEDs), which are known as unusual electroencephalogram (EEG) patterns, are described in a patient who had stroke and seizures. This patient underwent Tc-99m HMPAO (hexamethyl propylene amine oxime) brain single photon emission computed tomography (SPECT) imaging both during PLEDs on EEG and after the cessation of PLEDs. The initial SPECT study reve...

This study aims to characterize and compare functional brain single photon emission tomography (SPECT) perfusion and connectivity in treatment-resistant depression (TRD) according to distinct demographic or clinical profiles (male vs. female; old vs. young; unipolar vs. bipolar) and to study their relationship to the severity and the duration of episode/illness. We retrospectively included 127 ...

Introduction: The purpose of this study is to assess the integrated role of scintigraphy by Tc99m MIBI in diagnosis of parathyroid adenoma and its impacts on the myocardium, and to evaluate whether myocardium perfusion gated SPECT study could be a complementary routine workup for patient with positive parathyroid adenoma on Tc99m MIBI parathyroid scan. Methods: Rest myocardium perfusion gated ...

OBJECTIVES Patients with idiopathic REM sleep behavior disorder (IRBD) are at risk for developing Parkinson disease (PD) and dementia with Lewy bodies (DLB). We aimed to identify functional brain imaging patterns predicting the emergence of PD and DLB in patients with IRBD, using SPECT with (99m)Tc-ethylene cysteinate dimer (ECD). METHODS Twenty patients with IRBD were scanned at baseline dur...

UNLABELLED Multimodality visualization aims at efficiently presenting integrated information obtained from different modalities, usually combining a functional modality (SPECT, PET, functional magnetic resonance imaging) with an anatomical modality [CT, magnetic resonance imaging (MRI)]. This paper presents a technique for three-dimensional integrated visualization of SPECT and magnetic resonan...

Background: The standard treatment for locally advanced non-small cell lung cancer (LA-NSCLC) is represented by concomitant chemo-radiotherapy followed consolidation with durvalumab that ensures a 5-year survival of 46%. However, the risk radiotherapy-induced pneumonia (RIP) almost 10–15%. Complete cardiological examination also usually performed during cardiopulmonary pre-treatment evaluation ...

In this paper we propose a new diagnostic feature for Alzheimer's Disease (AD) which is based on assessment of the degree of inter-hemispheric asymmetry using Single Photon Emission Computed Tomography (SPECT). The asymmetry measure used represents differences in 3D perfusion image patterns in the cerebral hemispheres. We start from the simplest descriptors of brain perfusion such as the mean i...

Occlusion of the common carotid artery (CCA) is rare. CCA occlusion (CCAO) can present as drowsiness and right hemiplegia related to emboli after total arch replacement. Although we selected a follow-up at first because color duplex sonography showed retrograde flow from the left external carotid artery to the internal carotid artery, this patient had epilepsy and single-photon emission compute...

UNLABELLED Detecting perfusion interhemispheric asymmetry in neurologic nuclear medicine imaging is an interesting approach to epilepsy. METHODS This study compared 4 methods that detect interhemispheric asymmetries of brain perfusion in SPECT. The first (M1) was conventional side-by-side expert-based visual interpretation of SPECT. The second (M2) was visual interpretation assisted by an int...