نتایج جستجو برای: bovine lactoferrin
تعداد نتایج: 76071 فیلتر نتایج به سال:
BACKGROUND Cure rates for eradication of Helicobacter pylori appear to be decreasing, thus more effective therapies must be identified. AIM To evaluate the efficacy of bovine lactoferrin in the treatment of H. pylori infection. METHODS In a multicentered prospective study, 402 (mean age 52.4, range 19-84 years) H. pylori-positive patients were assigned to one of three regimens: group A - es...
Lactoferrin is an important biological molecule with many functions such as modulation of the inflammatory response, iron metabolism and antimicrobial defense. One effect of lactoferrin is the inhibition of the classical complement pathway. This study reports that antimicrobial peptides derived from the N-terminal region from both human and bovine lactoferrin, lactoferricin H and lactoferricin ...
Bovine lactoferrin inhibits the clearance of remnant lipoproteins from the plasma and competes with the cell-surface binding of apolipoprotein (apo) E-enriched remnants. We established that lactoferrin inhibits remnant binding and uptake by interacting with both heparan sulfate proteoglycans (HSPG) and the low-density lipoprotein receptor-related protein (LRP). The binding of 125I-lactoferrin w...
The iron-binding protein lactoferrin is a ubiquitous and abundant constituent of human exocrine secretions. Lactoferrin inhibits bacterial growth by sequestering essential iron and also exhibits non-iron-dependent antibacterial, antifungal, antiviral, antitumor, anti-inflammatory, and immunoregulatory activities. All of these non-iron-dependent activities are mediated by the highly charged N te...
In this study, bovine lactoferrin (bLf), an iron-binding glycoprotein considered an important nutraceutical protein because of its several properties, was expressed in Pichia pastoris KM71-H under AOX1 promoter control, using pJ902 as the recombinant plasmid. Dot blotting analysis revealed the expression of recombinant bovine lactoferrin (rbLf) in Pichia pastoris. After Bach fermentation and pu...
Bovine colostrum (BC) is the initial milk produced by cows after giving birth. It has been used to treat human diseases, such as infections, inflammations, and cancers. Accumulating evidence suggests that bovine lactoferrin antibodies seem be most important bioactive constituents in BC. Thus, BC also reviewed for its potential deliver short-term protection against coronavirus disease 2019 (COVI...
Lactoferrin (Lf) is an iron-binding glycoprotein which exhibits antibacterial activity against a broad range of Gram-negative and Gram-positive bacteria. The mechanisms of this property are complex and involve iron sequestration as well as direct interaction with bacteria. Lactoferricin (LFcin), a Lf-derived peptide released by pepsin digestion of lactoferrin, is a more potent antibacterial com...
ThirtyFrieswal lactating cows were screened for clinical and subclinical mastitis and subsequently classified into healthy, subclinically affected and clinically affected groups each group comprising of 10 cows. Polymorphism of cow lactoferrin (LTF) gene promoter was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The results showed that LFT gene pro...
lactoferrin (lf) is a bioactive protein present in all external secretions such as milk that plays important role in the innate host defense. therefore, the lf has a major role in bovine mammary gland defense during mastitis. in this study, 5’-flanking region of bovine lf gene containing three single nucleotide polymorphisms (snps) at positions −602 (t/g), −600 (a/g) and -586 (t/c) were screene...
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