Spasticity or increase in muscle tone is one of the problems following stroke. Due to this increase in muscle tone, patients are confronted to problems in motor control and difficulties in activities of daily living and complications such as shortness and contracture. The aim of this study is to compare the effects of using splint or botulinum toxin injection on spasticity, range of motion and ...

Clostridium botulinum comprises a diverse group of botulinum toxin-producing anaerobic rod-shaped spore-forming bacteria that are ubiquitously distributed in soils and aquatic sediments. Decomposition of plants, algae, and animals creates anaerobic environments that facilitate growth of C. botulinum, which may then enter into food webs leading to intoxication of animals. Via saprophytic utiliza...

purpose : the aim of this study is to evaluate the effectiveness of intraoperative botulinum toxin-a (bta) injection as an adjunct to the surgical treatment of large-angle esotropia or exotropia. methods : thirteen patients were included in this interventional case series study. mean age of the patients was 23.31±13.29 years (range: 5-43 years). of these 13 patients, 6 were exotropic and 7 were...

background: achalasia is the most recognized esophageal motor disorder with an unknown etiology. symptoms rather than physical findings are hallmarks of the disease. modalilies for treatment include pharmacologic, botulinum toxin injection, pneumatic dilation and surgery. materials and methods: to review the diagnostic and therapeutic options currently available for achalasia. a medline search ...

In this article, the evidence base for botulinum-A treatment acquired in recent years is outlined, and the practicalities involved in providing this service are described. Botulinum-A is relatively new, and possible improvements for the future are considered.

Botulinum toxin is significantly associated with decreased spasticity, increased range of motion and improved upper extremity function. Botulinum toxin in combination with electrical stimulation improves upper extremity function. Deinnervation of the subscapularis muscle using botulinum toxin may reduce shoulder pain and improve passive range of motion, more so than deinervation of the pectoral...

Background—Botulinum toxin A is a potent inhibitor of the release of acetylcholine from nerve endings. Local injection of botulinum toxin has recently been suggested to be helpful in sphincter of Oddi dyskinesia by decreasing sphincter of Oddi pressure. Aims—To explore the mechanism of action of botulinum toxin A on sphincter of Oddi (SO) muscle. Methods—Four piglets underwent duodenoscopy and ...

A retrospective study of Clostridium botulinum strains isolated from patients from California with infant botulism identified the fourth known C. botulinum strain that produces both type B and type F botulinum toxins. This unique strain represented 0.12% of the California infant botulism case isolates from 1976 to 2003. The relative concentrations of type B and F toxins produced were temperatur...

BACKGROUND Intrasphincteric injection of botulinum toxin is a new treatment option for achalasia. AIMS To compare the immediate and long term efficacy of botulinum toxin with that of pneumatic dilatation. METHODS Symptomatic patients with achalasia were randomised to botulinum toxin (22 patients, median age 57 years) or pneumatic dilatation (20 patients, median age 56 years). Symptom scores...