Fig. 6 Effects of BA upon hepatic inflammation, determined by H&E stain, in mice with BA at 0, 0.05 or 0.1% for 4 weeks, and followed by APAP treatment. Normal groups had neither BA nor APAP treatments. BA groups had 0.1% BA intake without APAP treatment. Ishak inflammation score was used to quantify the injury area. Values are mean ± SD, n = 10. A representative image is shown for each group. ...

OBJECTIVES Boswellic acid (BA), a compound isolated from the gum-resin of Boswellia carterii, is a pentacyclic terpenoid that is active against many inflammatory diseases, including cancer, arthritis, chronic colitis, ulcerative colitis, Crohn's disease, and memory impairment, but the mechanism is poorly understood. This study investigated the effects of boswellic acid on spatial learning and m...

Background: Osteoarthritis (OA) incidence has skyrocketed in the last decade and yet a definitive treatment still to be found. This worldwide disease is depriving our society from their life quality become grave economic burden. Research on anti-inflammatory tools been done traditional Asian medicine. Boswellic acid plant-derived molecule Boswellia species that shown prevent cartilage loss an O...

In the course of our ongoing search for new natural products as leads against protozoal diseases, the dichloromethane extract of Indian frankincense, the oleo-gum-resin obtained from Boswellia serrata, showed in vitro activity against Plasmodium falciparum. Bioactivity-guided fractionation led to the isolation of eight diterpenes: (1S,3E,7E,11R)-verticilla-3,7,12(18)-triene (1), cembrene A (2),...