نتایج جستجو برای: bone turnover

تعداد نتایج: 341303  

Journal: :Cancer research 2007
Yu Zheng Hong Zhou James R K Modzelewski Robert Kalak Julie M Blair Markus J Seibel Colin R Dunstan

The skeleton is a major site of breast cancer metastases. High bone turnover increases risk of disease progression and death. However, there is no direct evidence that high bone turnover is causally associated with the establishment and progression of metastases. In this study, we investigate the effects of high bone turnover in a model of breast cancer growth in bone. Female nude mice commence...

2009
Shota Ikegami Mikio Kamimura Hiroyuki Nakagawa Kenji Takahara Hiroyuki Hashidate Shigeharu Uchiyama Hiroyuki Kato

Healing of fractures is different for each bone and bone turnover markers may reflect the fracture healing process. The purpose of this study was to determine the characteristic changes in bone turnover markers during the fracture healing process. The subjects were consecutive patients with femoral neck or trochanteric fracture who underwent surgery and achieved bone union. There were a total o...

Journal: :The American Journal of Clinical Nutrition 2004

Journal: :Journal of biomechanics 2008
Timothy L Norman Tara M Little Yener N Yeni

It has been proposed that bone damageability (i.e. bone's susceptibility to formation of damage) increases with the elevation or suppression of bone turnover. Suppression of turnover via bisphosphonates increases local bone mineralization, which theoretically should increase the susceptibility of bone to microcrack formation. Elevation of bone turnover has also been proposed to increase bone mi...

Journal: :Environmental Health Perspectives 1991
M B Rabinowitz

This article discusses bone as a source of lead to the rest of the body and as a record of past lead exposure. Bone lead levels generally increase with age at rates dependent on the skeletal site and lead exposure. After occupational exposure, the slow decline in blood lead, a 5- to 19-year half-life, reflects the long skeletal half-life. Repeated measurements of bone lead demonstrate the slow ...

2008
J. E. Fonseca

This review updates our current knowledge on the mechanism of action of strontium ranelate and analyses the way it rebalances bone turnover and how it influences bone biomechanics. Strontium ranelate is able to increase pre-osteoblast replication, osteoblast differentiation, collagen type I synthesis and bone matrix mineralization probably through a calcium-sensing receptor (CaR)-dependent mech...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید