نتایج جستجو برای: bone plate

تعداد نتایج: 372779  

2017
D. Otsuki K. Yoshida M. Kobayashi D. Hamano C. Higuchi H. Yoshikawa

OBJECTIVES The purpose of this study is to evaluate the effects of allogenic costal cartilage transplantation on preventing bony bridge formation and angular deformities for the treatment of partial growth plate injury using a rabbit model. METHODS An experimental model of partial growth injury was created by resecting the medial part of the proximal tibial growth plate in male six-week-old N...

Journal: :American journal of physiology. Endocrinology and metabolism 2013
Stav Simsa-Maziel Janna Zaretsky Adi Reich Yoav Koren Ron Shahar Efrat Monsonego-Ornan

The proinflammatory cytokine interleukin-1 (IL-1) signals through IL-1 receptor type I (IL-1RI) and induces osteoclastogenesis and bone resorption mainly during pathological conditions. Little is known about the effect of excess or absence of IL-1 signaling on the physiological development of the growth plate and bone. In this study, we examine growth plate morphology, bone structure, and mecha...

2017
Bradley Campbell Patrick Schimoler Sudhir Belagaje M. C. Miller S. F. Conti

BACKGROUND This study sought to determine whether several metatarsophalangeal (MTP) fusion techniques require complete immobilization or if some level of weight-bearing could be recommended after surgery. A comparison of synthetic composite to actual bone was included in order to examine the validity of the testing conditions. METHODS Four MTP fusion modalities were tested in synthetic compos...

Journal: :Endocrinology 2000
F De Luca J A Uyeda V Mericq E E Mancilla J A Yanovski K M Barnes M H Zile J Baron

Vitamin A deficiency and excess both cause abnormalities in mammalian longitudinal bone growth. Because all-trans retinoic acid (RA) is synthesized from vitamin A, we hypothesized that RA regulates growth plate chondrogenesis. Consistent with this hypothesis, a single oral dose of RA reduced the height of the rat proximal tibial growth plate. To determine whether RA acts directly on growth plat...

Journal: :Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2010
Katsuhiko Okabe Koichiro Ueki Kohei Marukawa Aya Mukozawa Mao Miyazaki Kiyomasa Nakagawa

OBJECTIVE The purpose of this study was to histologically and immunohistochemically evaluate bone formation using both self-setting α-tricalcium phosphate (α-TCP; Biopex) and absorbable plate (Super Fixsorb-MX) in rabbit cranium bone. STUDY DESIGN Twelve adult male Japanese white rabbits (12-16 wk, 2.5-3.0 kg) were used. The surgical defects were made in the nasal bone of a rabbit, and Biopex...

Journal: :Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006
Xiaowei S Liu Paul Sajda Punam K Saha Felix W Wehrli X Edward Guo

UNLABELLED The roles of microarchitecture and types of trabeculae in determining elastic modulus of trabecular bone have been studied in microCT images of 29 trabecular bone samples by comparing their Young's moduli calculated by finite element analysis (FEA) with different trabecular type-specific reconstructions. The results suggest that trabecular plates play an essential role in determining...

2016
Haci Bayram Tosun Ismail Agir Seyitali Gumustas Sancar Serbest Abuzer Uludag Suat Celik

BACKGROUND There are many techniques that are used for limb lengthening. Lengthening a limb over a plate is an alternative choice used in children or when using an intramedullary nail is difficult. OBJECTIVES In this study, we presented a new technique for tibial lengthening using a monolateral external fixator over a lengthening plate. MATERIALS AND METHODS For tibial lengthening, a monola...

2011
Timothy A. Mirtz Judy P. Chandler Christina M. Eyers

BACKGROUND Children need physical activity and generally do this through the aspect of play. Active play in the form of organized sports can appear to be a concern for parents. Clinicians should have a general physiological background on the effects of exercise on developing epiphyseal growth plates of bone. The purpose of this review is to present an overview of the effects of physical activit...

2018
Katherine A. Staines Kamel Madi Behzad Javaheri Peter D. Lee Andrew A. Pitsillides

The epiphyseal growth plate is a developmental region responsible for linear bone growth, in which chondrocytes undertake a tightly regulated series of biological processes. Concomitant with the cessation of growth and sexual maturation, the human growth plate undergoes progressive narrowing, and ultimately disappears. Despite the crucial role of this growth plate fusion "bridging" event, the p...

Journal: :Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011
Xianrong Zhang Valerie A Siclari Shenghui Lan Ji Zhu Eiki Koyama Holly L Dupuis Motomi Enomoto-Iwamoto Frank Beier Ling Qin

Loss of epidermal growth factor receptor (EGFR) activity in mice alters growth plate development, impairs endochondral ossification, and retards growth. However, the detailed mechanism by which EGFR regulates endochondral bone formation is unknown. Here, we show that administration of an EGFR-specific small-molecule inhibitor, gefitinib, into 1-month-old rats for 7 days produced profound defect...

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