RANULOMATOUS LESIONS have been found iii paraffin sections nlade from particles of bone marrow removed by aspiration from patients w’it-h tuberculosis, histoplasmosis, brucehlosis, sarcoidosis, infectious mononucleosis, malignant lymphomas or miscellaneous and indeterminate disorders.19 In a previous paper,4 I discussed the significance of granulomatous lesions foiits(l in sections made from bo...

RANULOMATOUS LESIONS have been found iii paraffin sections nlade from particles of bone marrow removed by aspiration from patients w’it-h tuberculosis, histoplasmosis, brucehlosis, sarcoidosis, infectious mononucleosis, malignant lymphomas or miscellaneous and indeterminate disorders.19 In a previous paper,4 I discussed the significance of granulomatous lesions foiits(l in sections made from bo...

BACKGROUND Basal cell carcinoma (BCC) is the most common form of skin cancer and possesses various clinical features including translucency, ulceration, pigmentation, telangiectasia, and rolled borders. Accordingly, many cutaneous lesions can mimic BCCs and differential diagnosis is difficult. OBJECTIVE To clarify the differences in clinical characteristics between BCCs and BCC-mimicking lesi...

The aim of this study was to estimate the heritability and describe the correlates of bone marrow lesions in knee subchondral bone. A sibpair design was used. T2- and T1-weighted MRI scans were performed on the right knee to assess bone marrow lesions at lateral tibia and femora and medial tibia and femora, as well as chondral defects. A radiograph was taken on the same knee and scored for indi...

We compared MRI, CT and bone scintigraphy in the examination of experimentally produced metastatic bone tumors. Three Japanese white rabbits with VX-2 bone tumor were used. T1 weighted (T1W) and T2 weighted (T2W) images were obtained in each MRI examination. All the tumors distributed from the bone marrow to the extraosseous region. T2W images were the best to detect the extraosseous tumors. CT...

BACKGROUND AND PURPOSE Systematic investigations of the distinguishing imaging features between spinal hyperplastic hematopoietic bone marrow and bone metastasis have not been reported, to our knowledge. The purpose of this study was to determine the distinguishing imaging features of the 2 entities. MATERIALS AND METHODS We retrospectively reviewed the radiologic images of 8 consecutive male...

Bone is maintained by coupled activities of bone-forming osteoblasts/osteocytes and bone-resorbing osteoclasts. Alterations in this relationship can lead to pathologic bone loss such as osteoporosis. It well known that osteogenic cells support osteoclastogenesis via production RANKL. Interestingly, our recently identified marrow mesenchymal cell population—marrow adipogenic lineage precursors (...

Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...

Here we report imaging studies of a patient with pulmonary benign metastasizing leiomyoma (BML). A 44-year-old woman who underwent a hysterectomy for uterine cellular leiomyoma presented with abnormal shadows on a chest X-ray. Chest computed tomography (CT) revealed multiple well-defined nodules in both lungs. Chest magnetic resonance imaging (MRI) indicated these nodules as T1-low/T2-high inte...