Chronic recurrent multifocal osteomyelitis (CRMO) is a rare aseptic, auto-inflammatory bone disorder. CRMO presents with bone pain with or without fever. The diagnosis of CRMO is a diagnosis of exclusion and should be included in the differential diagnosis of chronic inflammatory bone lesions in children. Cultures of the bone are typically sterile, antibiotic therapy does not result in clinic...

ABSTRACT: Periodontitis is an inflammatory process of infectious origin affecting the teeth and their supporting structures, causing significant economic losses reducing animal welfare. Bacteria in gingival biofilm are one main factors initiating lesions. act directly on tissues or indirectly through substances that cause tissue damage. Studies etiopathogenesis periodontitis Brazilian sheep her...

Recently, an inverse role for Wnt signaling in the development of osteoclasts in the bone was demonstrated. In the present study, we examined whether there is a commonality in the mechanism of bone resorption and lysis that occur in a diverse set of bone metastatic lesions, as well as in primary bone lesions. Compared with control bone tissue and bone biopsies from patients with nonmetastatic p...

This paper presents four cases of abnormal soft tissue activity in the bone scan of patients with different lesions (lung inflammatory pseudotumor, pulmonary fibrosis, pulmonary metastatic osteosarcoma and metastatic hepatic carcinoma of colon).

Background: Oral lesions can affect people’s quality of life by impairment of chewing, swallowing and speech. These lesions may originate from epithelial or mesenchymal tissues. Malignant oral lesions could be life-threatening. Epidemiological data about oral lesions in our country is limited. Objective: This study was conducted to investigate the frequency of histopathologic features of oral ...

Pathologic fractures of the jaw are usually associated with aggressive, destructive lesions or malignant lesions of the jaws. Aneurysmal bone cysts (ABC) of the jaws are benign lesions which normally do not cause destruction to such an extent. This article reports a relatively aggressive ABC of the mandible in a 19 year-old male which destroyed the buccal and lingual cortices as well as th...

BACKGROUND Long-term severe hyperparathyroidism leads to thinning of cortical bone and cystic bone defects referred to as osteitis fibrosa cystica. Cysts filled with hemosiderin deposits may appear colored as "brown tumors." Osteitis fibrosa cystica and brown tumors are occasionally visualized as multiple, potentially corticalis-disrupting bone lesions mimicking metastases by bone scintigraphy ...

Introduction: Bone metastases are established when cancer cells reach the bone marrow through blood vessels in Haversian canals, extravasate, multiply, and eventually neovascularize. Metastatic bone lesions can be classified as osteolytic, osteoblastic and mixed. In osteolytic lesions, which are the most common, bone destruction outstrips the laying down of new bone. Osteoblastic lesions result...

The usefulness of bone marrow scintigraphy with 99mTc-HMPAO-labeled leukocytes (leukocyte bone marrow scintigraphy) in the diagnosis of skeletal metastases of cancers was investigated in 70 lesions in 27 patients with various types of cancer. The final diagnosis of skeletal metastases was based on one or more criteria consisting of histological confirmation, typical findings of metastases by bo...

BACKGROUND Choice of appropriate MR pulse sequence is important for any research studies using imaging-derived data. The aim of this study was to compare semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts using intermediate-weighted (IW) fat-suppressed (fs) spin echo and Dual Echo Steady State (DESS) sequences on 3 T MRI. METHODS Included were 201 ...