BACKGROUND The anti-osteoporotic drug raloxifene reduces the risk of vertebral fractures by increasing bone mass density. We investigated whether raloxifene offers any benefits in augmenting early fixation of orthopedic implants in the setting of impaction bone grafting. METHODS 24 non-weight-bearing grafted gap implants were inserted bilaterally into the tibia of 12 dogs. The 2.5-mm peri-imp...

The orthopedic foot and ankle surgeon needs bone grafts in the clinical situation of fracture healing and in bone-fusion procedures. This article briefly outlines thought processes and techniques for 2 recent options for the surgeon. The Trinity product is a unique combination of allograft bone and allograft stem cells. The beta-tricalcium phosphate and collagen materials provide an excellent s...

Bone loss around the knee in the setting of total knee arthroplasty remains a difficult and challenging problem for orthopaedic surgeons. There are a number of options for dealing with smaller and contained bone loss; however, massive segmental bone loss has fewer options. Small, contained defects can be treated with cement, morselized autograft/allograft or metal augments. Segmental bone loss ...

markedly elevated111 in labeled leukocyte activity suggestive of acute osteomyelitis was observed in a region of a composite mandibular allograft that was photon deficient on 99mtc mdp bone scintigraphy. this finding was later confirmed by surgical pathology. the patient was treated with intravenous antibiotics and returned two months later with persistent bone infection. the fohow-up three pha...

BACKGROUND Possible immunization to blood group or other antigens and subsequent inhibition of remodeling or incorporation after use of untreated human bone allograft was described previously. This study presents the immunological, clinical and radiological results of 30 patients with acetabular revisions using fresh frozen non-irradiated bone allograft. METHODS AB0-incompatible (donor-recipi...

The aim of limb-salvage surgery in malignant bone tumours in children is to restore function and eradicate local disease with as little morbidity as possible. Allografts are associated with a high rate of complications, particularly malunion at the allograft-host junction. We describe a simple technique which enhances union of allograft to host bone taking advantage of the discrepancy in size b...

RIDGE PRESERVATION COMPARING THE CLINICAL AND HISTOLOGIC HEALING OF A DEMINERALIZED PARTICULATE BONE ALLOGRAFT VS. MINERALIZED PARTICULATE CANCELLOUS ALLOGRAFT USING A PTFE BARRIER Veneta Kotevska, DDS

Objectives: Osteochondral allografts are used to treat chondral and osteochondral defects. While prior studies have correlated cell death within the component of directly with clinical outcomes, subchondral trabecular bone has not been well characterized. demonstrated a role for apoptosis in allografts, none examined pyroptosis necroptosis allografts. These pathways particular relevance because...

  Objective: Alveolar ridge preservation in patients with inadequate bone volume is one treatment option for successful implant placement and can be done by using bone graft materials. On the other hand, Ceno Bone has been recently produced by Hamanand Saz Baft Kish Co. as a bone bioimplant of allograft origin. This study aimed to assess the clinical, histologic and histomorphometric results of...