1 Hypothalamic gonadotropin releasing hormone (GnRH) receptor neurons fire in 2 synchrony with the female reproductive cycle 3 4 Abbreviated title: 5 GnRHR neuron activity during the estrous cycle 6 7 8 9 10 Christian Schauer1, Tong Tong1, Hugues Petitjean1, Thomas Blum1, Sophie Peron1, 11 Oliver Mai, Frank Schmitz, Ulrich Boehm, and Trese Leinders-Zufall 12 13 Department of Physiology and Cent...

The Spiral Model of software development [Boehm, 1988] begins each cycle of the spiral by performing the next level of elaboration of the prospective system's objectives, constraints, and alternatives. A primary difficulty in applying the spiral model has been the lack of explicit process guidance in determining these objectives, constraints, and alternatives. This paper presents an extension o...

Theme 1 Global software development: Developing information systems is a labor intensive and complex process that involves intense coordination of interdependent tasks. Current software engineering theory proposes several processes and methodologies for managing IS development (example: Boehm, 1988; Boehm, 2002; Humphrey, 1988; Humphrey, 1996; Paulk, et al., 1995). These processes and methodolo...

Historically CPM-GOMS has been used to predict total time for long stretches of behavior. In “Milliseconds Matter”, Gray and Boehm-Davis (2000) use CPM-GOMS to develop microstrategy variants with subtly different internal structure to explain differences observed in empirical data collected. They argue for microstrategies as the basic unit of adaptive behavior selection. While the microstrategi...

Macroeconomic analysis has been relatively neglected by Austrian economists since the beginning of the Austrian revival in the early 1960s with the publication of Murray N. Rothbard’s Man, Economy, and State (1993)1 and America’s Great Depression (2000). Rothbard’s treatise contained new and improved elaborations of the Austrian theories of money, capital, and business cycles. In particular Rot...

Parametric modeling and simulation can help reason about strategies for reducing defects by quantifying the impact of different processes and technologies. This paper presents our ongoing work to extend and refine the Constructive Quality Model (COQUALMO) for assessing defect dynamics to better understand the tradeoffs. Using parametric cost and defect removal inputs, static and dynamic version...

1. What exactly is an evidenced-based practice? It usually means an approach that has established itself better than placebo or treatment as usual in two clinical trials. Such demonstrations are nothing to write home about; intervention of nearly any kind has demonstrated its superiority over placebo for 50 years! This research tells us nothing that we already do not know: Treatment works. So, ...

This paper uses ALIS data to compare academic performance in two subjects often viewed as relatively close substitutes for one another at A-level. The important role of GCSE achievement is confirmed for both subjects. There is evidence of strong gender effects and variation in outcomes across Examination Boards. A counterfactual exercise suggests that if the sample of Business Studies candidate...

Parametric modeling and simulation can help reason about strategies for reducing defects by quantifying the impact of different processes and technologies. This paper presents our ongoing work to extend and refine the COnstructive QUALity MOdel (COQUALMO) for assessing defect dynamics to better understand the tradeoffs. Using parametric cost and defect removal inputs, static and dynamic version...