Di-(2-ethylhexyl) phthalate (DEHP) accumulates in blood brought into contact with materials utilizing this compound as a plasticizer. To determine whether this phthalate diester affects red blood cell integrity, we have compared cell morphology, plasma hemoglobin accumulation, micro-vesicle production, and the concentration of intracellular metabolites and electrolytes of erythrocytes from bloo...

Classification of the morphology red blood cells (RBCs) plays an extremely important role in evaluating quality long-term stored blood, as RBC storage lesions such transformation discocytes to echinocytes and then spherocytes may cause adverse clinical effects. Most segmentation classification methods, limited by interference staining procedures poor details, are based on traditional bright fie...

results there were no significant differences between the 4 groups in white blood cell count, hemoglobin, hematocrit, and esr at baseline (p > 0.05). the number of platelet units was remarkably higher, but the number of mpv and hco3 was considerably lower in patients with loss/ failure criteria. conclusions mpv is higher in the case of platelets destruction, and this is commonly observed in inf...

from 1996 to 2002, fifty three patients with major beta-thalassemia received allogeneic peripheral blood stem cell trans plantation (pbsct). median age was 6 years .twenty two were class i, 17 class ii and 14 class iii. all of the donors were hla-identical. conditioning regimen for class i and ii patients consisted of cyclophosphamide (cy) 50 mg/kg/day for 4 days + busulfan (bu) 3.5 mg/kg for 4...

cell based therapeutics is one of the most rapidly advancing medical fields, bringing together a range of fields including transplantation, tissue engineering and regeneration, biomaterials and stem cell biology. however, traditional cell-based therapeutics have many limitations, one of which is their harmful effects exhibited on healthy body cells due to their lack of specificity. nanomedicine...

background: gallium-66 (t1/2= 9.49 h) is an interesting radionuclide that has potential for positron emission tomography (pet) imaging of biological processes in intermediate to slow target tissue uptake. oxine has been labeled with this radioisotope in the form of [66ga]gallium chloride for its possible diagnostic properties. materials and methods: 66ga was produced in the 30 mev cyclotron (cy...

Dendritic cells are present in both lymphoid and non-lymphoid organs, which heterogenous group of nonphagocytic nonlymphoid immune accessory cells. Plasmacytoid dendritic cell (which has an eccentric nuclei) subset aid secreting high levels type 1 interferons by activation gaining like morphology, play important role antiviral immunity involved initiation development stages inflammatory respons...