Significant advancements in nonsurgical and surgical approaches to control bleeding in severely injured patients have also improved the treatment of critical trauma-related coagulopathy. Nonsurgical procedures such as angiographic embolization are progressively considered to terminate arterial bleeding from pelvic fractures. The disturbance of coagulation may aggravate bleeding and hamper surgi...

Bleeding from cancellous bone causes lamination within bone cement and at its prosthetic interfaces, and weakens the fixation of joint replacements. We examined the effects of anaesthesia and blood pressure on bleeding in human cancellous bone, and investigated the local response to freezing saline, 1:200,000 adrenaline and hydrogen peroxide. Spinal anaesthesia reduced cancellous bleeding by an...

The purpose of this investigation was to use a quantitative technique to evaluate the hemostatic properties of gelfoam and thrombin. To accomplish this, blood was drawn from dogs, labeled in vitro with 5tCr and then reinjected back into the donor dogs. When pulp exposures were made, all blood shed from the site was collected in 30 second intervals to allow calculation of the rate of bleeding. T...

Every year, thousands of patients develop deep vein thrombosis (DVT) and are at risk of pulmonary embolism after undergoing surgeries, particularly orthopedic procedures in the hips and legs. Although low-molecular-weight heparin is considered the standard therapy for DVT and other forms of venous thromboembolism, it is far from an ideal anticoagulant. Its drawbacks include the need for daily i...

UNLABELLED The management of variceal bleeding remains a clinical challenge with a high mortality. Standardisation in supportive and new therapeutic treatments seems to have improved survival within the last 25 years. Although overall survival has improved in recent years, mortality is still closely related to failure to control initial bleeding or early re-bleeding occurring in up to 30-40% of...

Rate of bleeding following aortic root replacement is reported in upto 24% of cases. Bleeding significant enough to require re-operation is reported in upto 4% of cases. We performed a modification of Cabrol patch to control bleeding from complicated aortic root replacement procedure. We used a perigraft - right-atrial fistula technique to control bleeding from aortic root area using a bovine p...