quinolones are a very important family of antibacterial agents that are widely prescribed for the treatment of infections in humans. since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and scientific interest. two major groups of compounds have been developed from the basic molecule: quinolones and naphthyridones. the 4-pyridone-3-...

during the last two decades, various medicinal plants have been studied for their possible antimicrobial activity to discover new antimicrobial agents capable of resolving problems such as the development of drug resistance in pathogenic microorganisms as well as the side effects of some present antibiotics. in this study, the antibacterial activity of methanolic extract of t. pubescens (rich i...

background and objective: uttarakhand region is less explored, but possess a great biodiversity. this diversity can be explored for isolation and characterization of new actinomycetes strains for seeking antimicrobial molecules. it can therefore be predicted that novel bioactive metabolite producing actinomycetes can be discovered to combat multidrug resistant bacterial pathogens. materials and...

background :   chitosan is unbranched polysaccharide composed of d-glucosamine and n-acetyl-d-glucosamine. chitosan, derived from shrimp shell, has broad antimicrobial properties against gram-negative, gram-positive bacteria and fungi.   methods :  chitosan was extracted from shrimp shell and studied for cell entrapment and anti-bacterial properties. the hydrogel chitosan was used as the beads ...

the genus verbascum l. belongs to the family scrophulariaceae and includes plants that have been used widely in traditional medicine for a long time. methanolic extracts of three verbascum species from flora of iran were in vitro screened for their possible antioxidant activities by three complementary test systems, namely dpph free radical-scavenging, metal chelating activity and β-carotene/li...

tilmicosin (tlm) is an important antibiotic in veterinary medicine with low bioavailability and safety. this study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization and antibacterial activity of three tlm-loaded lipid nanoparticles (tlm-lnps) including solid lipid nanoparticles (slns), nanostructured lipid carriers (nlcs) and lipid-core nanocapsu...

lactobacillus species play an important role in gastrointestinal (gi) tract function, intestinal microbiota balance, and the immune system activity by exerting a strong activity against many intestinal pathogens. the aim of this study was to isolate lactobacillus species from fecal samples, investigate their antimicrobial properties, and characterixe their bacteriocins encoding genes. 48 fecal ...

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cladophora and enteromorpha are the filamentous green-algal genuses that have a widespread distribution in caspian sea coast. the aim of this study was to assess the antimicrobial activities of cladophora and enteromorpha in south of caspian sea. antibacterial activities of hydroalcoholic extracts of five different gram negative and positive bacteria including staphylococcus aureus, bacillus su...

the aim study antibacterial effects of silver nanoparticles against resistant strains of e.coli bacteria.12 strains of e. coli strains arising urinary infection were isolated from hospitalized patient in zabolhospitals. minimum inhibitory concentration of winter cherry were determined by dilution method in various concentration on bacteria. the highest mic values was found to be 100ppm against ...