Children presenting neurological problems and a history of “not cried immediately at birth” are labeled to have cerebral palsy due birth asphyxia. Although this may be true in many situations, the presence some additional features help determine an alternate diagnosis. We present such case with A child asphyxia was as global developmental delay or by treating doctors. However, had certain dysmo...

PURPOSE To study the validity of urinary uric acid (UA) as a marker of perinatal asphyxia in term and premature infants. METHODS The urinary ratio of UA to creatinine (Cr) was obtained within 24 hours after birth in four groups of infants: 17 term infants and 18 premature infants with perinatal asphyxia, and 22 healthy term infants and 20 premature infants without perinatal asphyxia. Perinata...

Using a model of birth asphyxia, we previously reported significant structural and functional deficits in the diaphragm muscle in spiny mice, deficits that are prevented by supplementing the maternal diet with 5% creatine from mid-pregnancy. The long-term effects of this exposure are unknown. Pregnant spiny mice were fed control or 5% creatine-supplemented diet for the second half of pregnancy,...

BACKGROUND Asphyxia is considered an important cause of morbidity and mortality in neonates. This condition can affect many vital organs including the central nervous system and may eventually lead to death or developmental disorders. OBJECTIVES Considering the high prevalence of asphyxia and its adverse consequences, the present study was conducted to evaluate the risk factors for birth asph...

Birth asphyxia is often associated with a high seizure burden that is predictive of poor neurodevelopmental outcome. The mechanisms underlying birth asphyxia seizures are unknown. Using an animal model of birth asphyxia based on 6-day-old rat pups, we have recently shown that the seizure burden is linked to an increase in brain extracellular pH that consists of the recovery from the asphyxia-in...

The examination of birth asphyxia from a historical perspective presents several intriguing problems. First, of course, there is no satisfactory definition. Clinicians, biochemists and pathologists all seem to use the phrase, but a universal definition is lacking. Dr. Eastman of Hopkins called asphyxia "an infelicity of etymology" since the Greek derivation of asphyxia meant "without pulse." A ...

Objective: Asphyxia  is  a  major  cause  of  acute  mortality  and  chronic  neurologic  disability  in  neonates. We sought to  define  the  predictive  values  of  serum  concentrations  of  interleukin-1β  in  newborns  with perinatal asphyxia to see if there is a relation between interleukin-1β (IL-1β) levels to the short term neurological deficit.  Methods: This was a prospective (case-co...

Introduction It was nearly 150 years ago that an association between perinatal events and brain injury was first reported, claiming that “the act of birth does occasionally imprint upon the nervous and muscular systems of the infantile organism very serious and peculiar evils” [1]. While a great deal is now known about this association and the pathophysiology behind it, the quantification of th...

Background: Asphyxia is a condition in which newborn babies do not breathe spontaneously and regularly after birth; out of 120 million born with Asphyxia, nearly 1 these die because Asphyxia. This caused by fetal hypoxia the womb associated factors that arise pregnancy, labor, birth. The high number cases death infants can be lack knowledge mothers preventing causes during pregnancy to childbir...

BACKGROUND Severe birth asphyxia (apgar < 7 at the 5th minute of birth) is recognized as a hearing loss risk factor by the joint committee on infant hearing (JCIH). About half of the newborns with hearing loss do not indicate any sign and risk factor at birth. Accordingly, the joint committee recommended performance of hearing screening test in 2000, especially for babies born with risk factors...