BACKGROUND Epidermolysis bullosa is a group of diseases caused by mutations in genes for proteins responsible for cells' anchorage at the dermo-epidermal junction. Their common feature are dysfunctional or even absent connections between cells. The typical clinical sign is the formation of blisters, with possible excessive scarring, in response to minimal skin irritation. End stage renal diseas...

245 4. Salavastru CM, Sprecher E, Panduru M, et al. Recommended strategies for epidermolysis bullosa management in romania. Maedica (Buchar) 2013;8:200-5. 5. Elluru RG, Contreras JM, Albert DM. Management of manifestations of epidermolysis bullosa. Curr Opin Otolaryngol Head Neck Surg 2013;21:588-93. systemic antibiotics. Specifically, after determining the location, size, type, and severity of...

I Gibbs RB, Minus HR. Epidermolysis bullosa acquisita with electron microscopical studies. Arch Dermatol 1975;111:215-20. 2 Yaoita H, Briggaman RA, Lawlev IJ, P'rovost TI', Katz SI. Epidermolysis bullosa acquisita: ultrastructural and immunologic studies. J Invest Dermatol 1981;76:288-92. 3 Epstein JH. Pseudoporphyria and U'A suntan salons [Abstract]. PhotochemPhotobtol 1987;45:40S. 4 Diffev BL...

Epidermolysis bullosa is a genetic mechanobullous disease of the stratified squamous keratinizing epithelium that affects the skin and mucous membranes. Its primary feature is the formation of blisters after minor shearing trauma to the skin or mucous membranes that can result in debilitating, even life-threatening scarring. The disease presents special problems for the anesthesia provider beca...

Epidermolysis bullosa dystrophica is a rare hereditary disorder which presents significant anaesthetic problems. These include malnutrition and anaemia; electrolyte imbalance in severe cases; renal failure and amyloidosis in progressive disease; association with porphyria; a history of steroid therapy. Technical problems associated with the necessity to avoid trauma to the skin and mucous membr...

A knot polymer, poly[bis(2-acryloyl)oxyethyl disulphide-co-2-(dimethylamino) ethyl methacrylate] (DSP), was synthesized, optimized and evaluated as a non-viral vector for gene transfection for skin cells, keratinocytes. With recessive dystrophic epidermolysis bullosa keratinocytes (RDEBK-TA4), the DSP exhibited high transfection efficacy with both Gaussia luciferase marker DNA and the full leng...

an abnormally small oral orifice is defined as microstomia. microstomia may result from epidermolysis bullosa (eb), which consists of a group of disorders characterized by the presence of mechanical fragility of the skin with recurrent development of blisters and vesicles, resulting from minor mechanical friction or trauma. since such patients have a small oral aperture, it may be impossible to...

background and aim kindler syndrome is a subtype of epidermolysis bullosa with gingival fragility and periodontitis as common oral manifestations of these patients. because of the early onset and rapid progression of periodontitis in these patients, clinical management of their oral status is an important aspect of their multidisciplinary care and treatment case presentation we present a succes...