نتایج جستجو برای: bird schistosomes
تعداد نتایج: 24996 فیلتر نتایج به سال:
The objective of this review is to clarify aspects of immunological and biochemical adaptations of schistosomes to their intermediate and final mammalian hosts. Adaptations to the mammalian hosts are traced in relation to cercarial penetration of mammalian skin, glucose transport and metabolism. The unusual ability of schistosome surface membrane to escape immune recognition and damage are revi...
Schistosomiasis is a neglected tropical disease (NTD) caused by parasitic trematodes belonging to the Schistosoma genus. The mainstay of schistosomiasis control delivery single dose praziquantel (PZQ) through mass drug administration (MDA) programs. These programs have been successful in reducing prevalence and intensity infections. Due success MDA programs, has recently targeted for eliminatio...
Cercariae of bird schistosomes (genus Trichobilharzia) are able to penetrate the skin of mammals (noncompatible hosts), including humans, and cause a Th2-associated inflammatory cutaneous reaction termed cercarial dermatitis. The present study measured the antibody reactivity and antigen specificity of sera obtained after experimental infection of mice and natural infection of humans. Sera from...
INTODUCF1ON SCHISTOSOMES that infect domestic animals are of great economic importance, and may even cause death in cattle and sheep.' These parasites may also at times infest man, the most important of the several species being Schistosoma haematobium and Schistosoma mansoni. They are the subject of the present discussion. Both these parasites have a complicated, but similar, life cycle. Matur...
Schistosomiasis is the most important helminthic disease of humanity in terms of morbidity and mortality. Facile manipulation of schistosomes using lentiviruses would enable advances in functional genomics in these and related neglected tropical diseases pathogens including tapeworms, and including their non-dividing cells. Such approaches have hitherto been unavailable. Blood stream forms of t...
Schistosomes are blood-dwelling trematodes with global impact on human and animal health. Because medical treatment is currently based on a single drug, praziquantel, there is urgent need for the development of alternative control strategies. The Schistosoma mansoni genome project provides a platform to study and connect the genetic repertoire of schistosomes to specific biological functions es...
Functional studies will facilitate characterization of role and essentiality of newly available genome sequences of the human schistosomes, Schistosoma mansoni, S. japonicum and S. haematobium. To develop transgenesis as a functional approach for these pathogens, we previously demonstrated that pseudotyped murine leukemia virus (MLV) can transduce schistosomes leading to chromosomal integration...
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