OBJECTIVES Bipolar disorder and schizophrenia share common pathophysiological processes and may have similar perceptual abnormalities. Mismatch negativity (MMN) and P3a - event-related potentials associated with auditory preattentional processing - have been extensively studied in schizophrenia, but rarely in bipolar disorder. Furthermore, MMN and P3a have not been examined between diagnostic s...

Treatment of Bipolar Depression Depressive episodes are significant in bipolar illness since patients can spend up to one-third of their lives in depression. Although the treatment of bipolar depression remains an understudied area, new data from randomized, controlled trials and naturalistic studies expanded the range of treatments avaliable. The main aim in the treatment of bipolar depression...

TO THE EDITOR Hair loss or hair color change in patients taking valproate has been repeatedly reported. However, drug-induced hair texture changes have been reported rarely. Curly hair is a very rare side effect of valproate. Valproate is recommended for the acute treatment of mania and maintenance of bipolar disorder as a mood stabilizer. Valproate can be used also in the treatment of epilepsy...

According to literature, genital self-mutilation (GSM) is more commonly associated with psychosis as compared with self-mutilation as a whole. There have been many case reports of GSM in psychotic disorders. We describe herein a case of a Caucasian, employed, and married male suffering from bipolar disorder type II with history of self-mutilating behavior, who amputated his penis during symptom...

INTRODUCTION Simultaneous bipolar dislocation of the clavicle is uncommon and unusual, although it has been documented as panclavicular dislocation, floating clavicle, and complete dislocation of the clavicle. A review of the recent literature indicated that most bipolar clavicular dislocations have been treated non-operatively. CASE REPORT We report the case of a 23 year polytrauma patient w...

Introduction: Simultaneous bipolar dislocation of the clavicle is uncommon and unusual, although it has been documented as panclavicular dislocation, floating clavicle, and complete dislocation of the clavicle. A review of the recent literature indicated that most bipolar clavicular dislocations have been treated non-operatively. Case Report: We report the case of a 23 year polytrauma patient w...

Egypt. J. Psychiatry, Jan 2009; 29(1): 35-42 Background: Associations between Eating Disorders (ED) and affective disorders have often been suggested in several epidemiological studies. There is a need to elucidate such comorbidity, as it can cause many risks to the patient. These risks can not only cause the patient to suffer further with bipolar disorder, but they can also do damage to the bo...

BACKGROUND Schizophrenia and bipolar disorder are severe mental disorders with overlapping genetic and clinical characteristics, including cognitive impairments. An important question is whether these disorders also have overlapping neuronal deficits. AIMS To determine whether large-scale brain networks associated with working memory, as measured with functional magnetic resonance imaging (fM...

OBJECTIVE Bipolar disorder is a heritable disorder characterized by mood dysregulation associated with brain functional dysconnectivity. Previous research has focused on the detection of risk- and disease-associated dysconnectivity in individuals with bipolar disorder and their first-degree relatives. The present study seeks to identify adaptive brain connectivity features associated with resil...

Studies have suggested that a ketogenic diet is beneficial for epilepsy, both in adults (1) and in children (2). As antiseizure medications have proved to be effective treatment for bipolar disorder, the question has arisen whether the ketogenic diet, or other diets, may be effective in the treatment of bipolar disorder (3). Dietary omega-3 fatty acids have been found to lengthen remissions in ...