نتایج جستجو برای: biomimetic

تعداد نتایج: 8027  

Journal: :Acta biomaterialia 2010
Jongryul Kim Dwayne D Arola Lisha Gu Young Kyung Kim Sui Mai Yan Liu David H Pashley Franklin R Tay

Natural biominerals are formed through metastable amorphous precursor phases via a bottom-up, nanoparticle-mediated mineralization mechanism. Using an acid-etched human dentin model to create a layer of completely demineralized collagen matrix, a bio-inspired mineralization scheme has been developed based on the use of dual biomimetic analogs. These analogs help to sequester fluidic amorphous c...

2015
Sagar N Kaushik Jessica Scoffield Adinarayana Andukuri Grant C Alexander Taneidra Walker Seokgon Kim Sung Chul Choi Brigitta C Brott Paul D Eleazer Jin-Yong Lee Hui Wu Noel K Childers Ho-Wook Jun Jae-Hong Park Kyounga Cheon

BACKGROUND A triple antibiotic mixture (ciprofloxacin; CF, metronidazole; MN, and minocycline; MC) has been used for dental root canal medicaments in pulp regeneration therapy. However, tooth discolorations, cervical root fractures, and inadequate pulp-dentin formation have been reported due to the triple antibiotic regimen. Therefore, an antibiotic encapsulated biomimetic nanomatrix gel was de...

2014
Quan-Li Li Tian-Yun Ning Ying Cao Wei-bo Zhang May Lei Mei Chun Hung Chu

BACKGROUND Researchers are looking for biomimetic mineralization of ena/mel to manage dental erosion. This study evaluated biomimetic mineralization of demineralized enamel induced by a synthetic and self-assembled oligopeptide amphiphile (OPA). RESULTS The results showed that the OPA self-assembled into nano-fibres in the presence of calcium ions and in neutral acidity. The OPA was alternate...

2002
Weiyuan John Kao Yiping Liu

1. Abstract 2. Introduction 3. Materials and Methods 3.1. Synthesis of polymer substrates containing biomimetic oligopeptides 3.2. In vitro macrophage and FBGC assays 3.3. In vivo cage implantation study 3.4. Statistical analysis 4. Results and Discussions 4.1. In vitro macrophage adhesion and FBGC formation 4.2. In vivo macrophage adhesion and FBGC formation 4.3. Probing the intracellular sign...

Journal: :Journal of the Royal Society, Interface 2014
David W Green Tazuko K Goto Kye-Seong Kim Han-Sung Jung

Materials chemistry is making a fundamental impact in regenerative sciences providing many platforms for tissue development. However, there is a surprising paucity of replacements that accurately mimic the structure and function of the structural fabric of tissues or promote faithful tissue reconstruction. Methodologies in biomimetic materials chemistry have shown promise in replicating morphol...

Journal: :Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 2003

Journal: :Beilstein Journal of Nanotechnology 2011

Journal: :Journal of Oral Research and Review 2018

2012
Ming-Guo Ma Run-Cang Sun

Biominerals and biomaterials with unique microstructure are mainly consisted of organic and inorganic materials, and exhibit excellent biological and mechanical properties. The formation mechanism of biomineral indicated that the organic matrixes have an important influence on the morphology and structure of the inorganic matrix material in the process of biomineralization. However, the biomine...

Journal: :HFSP journal 2008
Guy Rachmuth Chi-Sang Poon

Neuromorphic analog metal-oxide-silicon (MOS) transistor circuits promise compact, low-power, and high-speed emulations of iono-neuronal dynamics orders-of-magnitude faster than digital simulation. However, their inherently limited input voltage dynamic range vs power consumption and silicon die area tradeoffs makes them highly sensitive to transistor mismatch due to fabrication inaccuracy, dev...

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