Scientifically valid exposure assessment is crucial to risk assessment, risk management, and prevention of environmental disease. Scientists have used three tools to assess exposure: exposure history/questionnaire, environmental monitoring (including personal monitoring), and biological monitoring. Combinations of these tools usually provide the exposure information needed to meet objectives of...

Numerous compounds are continuously released into the environment during their production and use. The resulting mixtures contaminate the environment and can be a potential threat to organisms including man. Monitoring programmes are designed to assess levelsof individual compounds and mixtures in various compartments of the environment. Such levels depend on the release rate and the environmen...

We describe here a simple, fast, and reliable bioassay method for therapeutic drug monitoring of voriconazole. Fifty-eight clinical and external quality control samples were evaluated with this microbiological assay, and results were compared with those obtained with a previously validated chromatographic method. A good correlation between both assays was observed. This particular microbiologic...