Over the last 10 years, fluorescent semiconductor QD (quantum dot)-biomolecule conjugates have emerged as a powerful new sensing platform showing great potential in a wide range of applications in biosensing, environmental monitoring and disease diagnosis. The present mini-review is a brief account of the recent developments in QD-NA (nucleic acid), particularly NA aptamer, conjugate-based bios...

A novel bioconjugate of stearic acid capped maghemite nanoparticle (gamma-Fe(2)O(3)) with bovine serum albumin (BSA) was developed by taking recourse to the fatty acid binding property of the protein. From FT-IR study, it was found that conjugation took place covalently between the amine group of protein molecule and carboxyl group of stearic acid capped maghemite nanoparticle. TEM study furthe...

Hybridbio/-synthetic sensory conjugated polymer nanoparticles (CPNs) are developed for selective label-free detection of target ssDNA in serum. Carboxylic acid-functionalized anionic polyfluorene nanoparticles are rationally designed as signal amplifying unit to bioconjugate with amine functionalized single stranded oligonucleotides as a receptor. The covalent DNA coating can significantly impro...

BACKGROUND Functionalized gold nanoparticles are emerging as a promising nanocarrier for target specific delivery of the therapeutic molecules in a cancer cell, as a result it targeted selectively to the cancer cell and minimized the off-target effect. The functionalized nanomaterial (bio conjugate) brings novel functional properties, for example, the high payload of anticancer, antioxidant mol...

One of the methods for treating oncological diseases is application short-lived radionuclides. Existing risks intoxication and radioactive contamination can be eliminated by introduction a radon isotope into hard strong fullerene coat. To increase effectiveness these drugs it promising to introduce structural fragments amino acids, peptides, steroid hormones, nucleic bases or heterocyclic compo...

We report the fabrication of a coaxial electrospun scaffold with bioactive molecule in core and protein conjugated at surface. To construct scaffold, we chose polyethylene oxide for material polycaprolactone/Jeffamine blend shell.