background: campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. the aim of this study was to compare the species distribution and antimicrobial susceptibility pattern of campylobacter spp. strains isolated from patients and f...

Screening of biochemical interactions becomes simpler, less expensive, and more accurate when labels, such as fluorescent dyes, radioactive markers, and colorimetric reactions, are not required to quantify detected material. SRU Biosystems has developed a biosensor technology that is manufactured on continuous sheets of plastic film and incorporated into standard microplates and microarray slid...

Aims: The membrane associated tyrosinase is an enzymatically active monomeric glycoprotein which purified to only a low degree. It has gained importance in the present era due its antioxidant and immunomodulatory properties as well applications industry. Moreover role synthesis of melanin skin for protection from UV radiations also paved way towards better understanding this enzyme.
 Study...

The objective of this study was to determine whether the nadir value of serum prostate-specific antigen (PSA) measured by an ultrasensitive assay could be a useful predictor of biochemical recurrence after radical prostatectomy for clinically localized prostate cancer. This study included 127 patients who underwent radical prostatectomy for clinically localized prostate cancer without neoadjuva...

escherichia coli o157:h7 is an important human pathogen causing haemorrhagic colitis, haemolyticuraemic syndrom and thrombotic thrombocytopenic purpura. in this study, 100 ground beef samples were collected randomly from beef markets in june 2004. for isolation of the bacteria, samples were firstly enriched in modified trypticase soy broth, followed by plating onto sorbitol macconkey agar suppl...

The Ubiquitin Proteasome Pathway (UPP) has become a target rich pathway for therapeutic intervention as its role in pathogenic disease is better understood. In particular many E3 ligases within this pathway have been implicated in cancer, inflammation and metabolic diseases. It has been of great interest to develop biochemical assays to identify inhibitors of catalytic E3 ubiquitination activit...

Enzymes of essential amino acid biosynthesis pathways are the targets of choice for drug discovery as these pathways are absent in mammals. Inhibitors of these enzymes will have reduced toxicity problems for the vertebrate host organisms. The histidine biosynthesis pathway is an important biochemical pathway found in bacteria, archebacteria, fungi and plants but absent in human. In recent times...

Corynebacterium jeikeium causes systemic infections, particularly in immunocompromised hosts. A minitube assay has been developed for the presumptive identification of C. jeikeium. With our rapid sucrose-urea test and conventional biochemical tests, sixty isolates of gram-positive, catalase-positive bacilli were identified in our laboratory. Results indicated that our assay has a sensitivity of...