Electrospray ionization mass spectrometry (ESI-MS) conditions were optimized for simultaneous observation of a bimolecular qDNA and a Watson-Crick base-paired duplex DNA/RNA hybrid. The DNA sequence used was telomeric DNA, and the RNA contained the template for telomerase-mediated telomeric DNA synthesis. Addition of RNA to the quadruplex DNA (qDNA) resulted in formation of the duplex DNA/RNA h...

The principle of controlling atomic and molecular processes via quantum interference, i.e. coherent control, is now well established.1,2 In particular, one arranges to arrive at a Ðnal state through two or more independent coherent routes whose features can be varied via experimentally controllable parameters. Having done so, the multiple routes, and the interference between them, can be contro...

The reaction A + B −→ B is studied when the reactants diffuse in phase space, i.e. their dynamics is described by the Langevin equation. The steadystate rate constants are calculated for both the target (static A and mobile B’s) and trapping (mobile A and static B’s) problems when the reaction is assumed to occur at the first contact. For Brownian dynamics (i.e., ordinary diffusion), the rate c...