background: inhibitory antibody to exogenous factor viii (fviii) is a major complication of hemophilia treatment. this study was conducted to determine the prevalence of inhibitor antibody directed against fviii.methods: from may 2010 to may 2011, 52 patients with severe hemophilia a admitted in amirkola children’s hospital were evaluated. those who had abnormal mixing study, antibody against f...

OBJECTIVE Several molecular marker tests are available to refine the diagnosis of thyroid nodules. Knowing the true prevalence of malignancy (PoM) within each cytological category is considered necessary to select the most appropriate test and to interpret results accurately. We describe our institutional PoM among cytological categories and report our experience with molecular markers. DESIG...

INTRODUCTION Thyroid swelling is common problem among South Asian women. Although benign nodules far outnumber cancerous lesions, the risk of malignancy needs to be evaluated preoperatively for which fine needle aspiration cytology (FNAC) is widely used. Bethesda system for reporting thyroid cytopathology (BSRTC) was introduced to streamline the reporting of thyroid aspirates. We aimed to evalu...

1Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD; 2Department of Critical Care Medicine, NIH Clinical Center, Bethesda, MD; 3Metabolism Branch, National Cancer Institute (NCI), Bethesda, MD; 4Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD; 5Laboratory of Pathology, NCI, Bethesda, MD; 6Amgen, ...

: The Papanicolaou (Pap) smear used worldwide for cervical screening was developed by Dr George in 1940s. Pap is a simple, safe and effective test to detect cancer at an early stage. To study the spectrum of lesions based on Bethesda System(TBS) 2014 determine frequency premalignant malignant lesions. present prospective included 200 cases above 20 years age. cytological interpretation smears w...